Granted Patent
B2
US 8,097,253 · App. 12/271,825 · Granted Jan 17, 2012
Methods for inhibiting angiogenesis
Assignee:
University of Utah Research Foundation
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Abstract
The present invention provides methods and compositions for modulating proliferation, differentiation, migration, and adhesion of cardiovascular cell types.
Claims (1)
1. A method for inhibiting angiogenesis in a subject in need thereof, comprising administering an antibody that binds a netrin1 polypeptide, in an amount effective to inhibit angiogenesis, wherein said netrin1 polypeptide comprises the amino acid sequence SEQ ID NO: 2 or SEQ ID NO: 4, and wherein said antibody inhibits the angiogenic activity of said netrin1 polypeptide.
Assignments (1)
CONFIRMATORY LICENSE
Recorded Oct 20, 2015
From: UNIVERSITY OF UTAH
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 036897/0912 →
Continuity (3)
Provisional Application
60587796
· Jul 14, 2004