Methods and compositions for the treatment of Parkinson's Disease
The invention features methods and kits for treating or inhibiting the development of Parkinson's Disease by administering 7-chloro-4-aminoquinoline compounds, e.g., amodiaquine or glafenine. Stem cells are also useful in the methods of the invention and may be administered separately from or together with 7-chloro-4-aminoquinoline compounds. The invention further features methods of identifying additional chemical compounds that are useful in the treatment or inhibition of the development of Parkinson's Disease.
1. A method for treating or inhibiting the development of Parkinson's Disease comprising the steps of:
(a) determining whether a patient has or is at risk of developing Parkinson's Disease; and
(b) if said patient has or is at risk of developing Parkinson's Disease, administering to said patient a pharmaceutical composition comprising amodiaquine in an amount sufficient to treat or inhibit the development of Parkinson's Disease and a pharmaceutically acceptable excipient.