IP Library Granted Patent US 8,121,368
Granted Patent B2
US 8,121,368 · App. 12/291,829 · Granted Feb 21, 2012

3D real-time tracking of human anatomy using combined kV and MV imaging

Assignee: The Board of Trustees of the Leland Stanford Junior University
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Quick Facts
Patent No.
US 8,121,368
App. No.
12/291,829
Granted
Feb 21, 2012
Kind
B2
Abstract

A medical imaging-based system and method uses both kV and MV images captured during a treatment period for organ motion tracking. 3D geometric locations of internal features are computationally tracked as a function of time from internal features, such as natural biological features or implanted fiducials, which are computationally extracted from the captured kV and MV images. A partial information method allows 3D tracking to be maintained in the event that imaging information is temporarily not available.

Claims (20)

1. A medical imaging-based method for organ motion tracking as a function of time, the method comprising:

capturing kV images during a treatment period using a kV imaging detector;

capturing MV images during the treatment period using an MV radiotherapy beam imaging detector;

extracting 2D kV projection locations of internal features from the captured kV images;

extracting 2D MV projection locations of the internal features from the captured MV images;

combining the extracted 2D kV projection locations and extracted 2D MV projection locations with information describing geometry of the kV imaging detector and MV radiotherapy beam imaging detector to calculate 3D locations of the internal features; and

computationally tracking 3D geometric locations of the internal features as a function of time from the 3D locations of the internal features and information of previous positions of the internal features.

2. The method of claim 1 wherein the capturing kV images comprises capturing the kV images continuously during the treatment period.

3. The method of claim 1 wherein the capturing kV images comprises capturing the kV images intermittently during the treatment period.

4. The method of claim 1 wherein the internal features are natural biological features.

5. The method of claim 1 wherein the internal features are implanted fiducials.

6. The method of claim 1 wherein the kV imaging detector is a kV diagnostic imaging detector.

7. The method of claim 1 wherein computationally tracking comprises using a partial information method.

8. A medical imaging system comprising:

a) kV and MV beam generators for generating kV and MV beams;

b) kV and MV x-ray detector arrays for detecting the kV and MV beams;

c) an image grabber to capture kV images and MV images acquired using the x-ray detector arrays, and

d) a computer for extracting 2D kV projection locations of the internal features from the kV images, extracting 2D MV projection locations of the internal features from the MV images, combining the extracted 2D kV projection locations and extracted 2D MV projection locations with information describing geometry of the kV imaging detector and MV radiotherapy beam imaging detector to calculate 3D locations of the internal features, computing continuous 3D geometric locations of internal features as a function of time from the 3D locations of the internal features and information of previous positions of the internal features.

9. The method of claim 8 wherein the kV and MV x-ray detectors are flat panel detectors.

10. The method of claim 8 wherein the image grabber is a hardware frame grabber.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jan 20, 2010
From: THE BOARD OF TRUSTEES OF THE THE LELAND STANFORD JUNIOR UNIVERSITY
To: US ARMY, SECRETARY OF THE ARMY
Reel/Frame 023813/0731 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 4, 2009
From: WIERSMA, RODNEY D.; XING, LEI; MAO, WEIHUA
To: BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE
Reel/Frame 022242/0074 →
Continuity (2)
Provisional Application 61066322 · Feb 19, 2008
Related Publication 20090208074A1 · Aug 20, 2009