IP Library Granted Patent US 8,207,131
Granted Patent B2
US 8,207,131 · App. 12/298,190 · Granted Jun 26, 2012

Peptide

Assignee: Megmilk Snow Brand Co., Ltd.
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Quick Facts
Patent No.
US 8,207,131
App. No.
12/298,190
Granted
Jun 26, 2012
Kind
B2
Abstract

The present invention relates to a peptide that is derived from a milk protein and has an antioxidative effect, an antioxidant that includes the peptide as an active ingredient, and an antioxidative food, drink, or feed that includes the peptide. The present invention also relates to a peptide that is derived from a milk protein and has an adiponectin production promotion effect, an adiponectin production promoter that includes the peptide as an active ingredient, and an adiponectin production promotion food, drink, or feed that includes the peptide. The present invention further relates to a blood adiponectin level increase promotion and/or decrease inhibition agent that includes a component contained in cheese as an active ingredient, and a blood adiponectin level increase promotion and/or decrease inhibition food or drink that includes a component contained in cheese. The present invention to the peptide that consists of an amino acid sequence shown by His-Pro-Ile-Lys-His-Gln-Gly-Leu-Pro-Gln (1), His-Pro-Ile-Lys (2) or His-Gln-Gly-Leu-Pro-Gln (3), and has an antioxidative effect.

Claims (6)

1. A method of promoting fat burning in a subject in need thereof, comprising administering to the subject an effective amount of an isolated peptide consisting of the amino acid sequence His-Pro-Ile-Lys-His-Gln-Gly-Leu-Pro-Gln (SEQ ID NO: 1).

2. A method of increasing the level, or suppressing a decrease in the level, of adiponectin in the blood of a subject in need thereof, comprising administering to the subject an effective amount of an isolated peptide consisting of the amino acid sequence His-Pro-Ile-Lys-His-Gln-Gly-Leu-Pro-Gln (SEQ ID NO: 1).

3. A method of promoting fat burning in a subject in need thereof, comprising administering to the subject an effective amount of an isolated peptide consisting of the amino acid sequence His-Pro-Ile-Lys (SEQ ID NO: 2).

4. A method of increasing the level, or suppressing a decrease in the level, of adiponectin in the blood of a subject in need thereof, comprising administering to the subject an effective amount of an isolated peptide consisting of the amino acid sequence His-Pro-Ile-Lys (SEQ ID NO: 2).

5. A method of promoting fat burning in a subject in need thereof, comprising administering to the subject an effective amount of an isolated peptide consisting of the amino acid sequence His-Gln-Gly-Leu-Pro-Gln (SEQ ID NO: 3).

6. A method of increasing the level, or suppressing a decrease in the level, of adiponectin in the blood of a subject in need thereof, comprising administering to the subject an effective amount of an isolated peptide consisting of the amino acid sequence His-Gln-Gly-Leu-Pro-Gln (SEQ ID NO: 3).

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 4, 2011
From: KUNIEDA, YUKIKO; HIGURASHI, SATOSHI; MOTOURI, MUTSUMI; MATSUYAMA, HIROAKI; SERIZAWA, ATSUSHI; KAWAKAMI, HIROSHI
To: SNOW BRAND MILK PRODUCTS CO., LTD.
Reel/Frame 026698/0638 →
MERGER Recorded Aug 4, 2011
From: SNOW MILK BRAND CO., LTD.
To: MEGMILK SNOW BRAND CO., LTD
Reel/Frame 026698/0750 →
Priority Claims (2)
JP 2006-125283 · Apr 28, 2006 · national
JP 2006-126103 · Apr 28, 2006 · national
Continuity (1)
Related Publication 20100075909A1 · Mar 25, 2010