IP Library › Granted Patent US 8,009,888
Granted Patent B2
US 8,009,888 · App. 12/307,673 · Granted Aug 30, 2011

Mobile device for particle analysis by image correlation

Assignee: Biophos AG
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,009,888
App. No.
12/307,673
Granted
Aug 30, 2011
Kind
B2
Abstract

The present invention refers to a mobile device for measuring dynamic parameters of particles, e.g. spermatozoa, such as the translation speed and the rotational speed of particles.

Claims (20)

1. A mobile device for measuring dynamic parameters of particles in a solution, the device comprises a sample compartment, a light source, an image sensor for generating a digital picture, a computational unit for processing the digital picture wherein the parameters are obtained by applying correlation analysis on temporal fluctuations of the number of particles with respect to a detection area of the digital picture, and that a time correlation function of functions is/are calculated based on the temporal fluctuations of the number of particles, and a means for displaying the calculations results.

2. The device of claim 1 , wherein the device is a mobile phone.

3. The device of claim 1 comprising an adapter module fitted thereto, wherein the adapter module comprises the sample compartment and optionally an additional optical element.

4. The device of claim 1 , wherein the sample compartment is a one-way sample compartment which is removably mounted on the mobile device or the adapter module.

5. The device of claim 1 , wherein the light source is an integrated mobile phone flash light source.

6. The device of claim 1 , wherein the image sensor is a CCD detector or a CMOS detector.

7. A mobile device for measuring dynamic parameters of particles in a solution, the device comprising a sample compartment, a light source, an image sensor for generating a digital picture, means for transferring the digital picture to a remote computational unit for processing the digital picture, wherein the parameters are obtained by applying correlation analysis on temporal fluctuations of the number of particles with respect to a detection area of the digital picture, and that a time correlation function of functions is/are calculated based on the temporal fluctuations of the number of particles; and a means for displaying the calculations results.

8. A method for measuring dynamic parameters of particles in a mobile device, wherein the method comprises:

providing a sample fluid comprising particles in solution,

introducing the sample into a sample compartment suitable for measurement in a mobile device,

generating a digital picture in a computational unit in the mobile,

processing the digital picture in a computational unit in the mobile phone or in a remote computational unit by applying correlation analysis on temporal fluctuations of the number of particles with respect to a detection area of the digital picture, and that a time correlation function of functions is/are calculated based on the temporal fluctuations of the number of particles; and displaying the results of the analysis in the mobile phone.

9. The method according to claim 8 , characterised in that the moving digital picture is generated by an image sensor.

10. The method according to claim 8 , characterised in that the correlation function is based on fluctuations of particles with respect to a plurality of detection areas.

11. The method according to claim 8 , characterised in that the image sensor is a CCD detector or a CMOS detector.

12. The method according to claim 8 , wherein the method further comprises background subtraction.

13. The method according to claim 8 , wherein the particles are spermatozoa.

14. The method of claim 8 , wherein the moving digital picture comprises a picture sequence of a plurality of several images, preferably at least 10 images.

15. The method of claim 8 , wherein the picture sequence is generated within a time of 0.5-1 0 sec, preferably 1-2 sec.

16. The method of claim 8 , wherein the mobile device comprises a sample compartment, a light source, an image sensor for generating a digital picture, a computational unit for processing the digital picture wherein the parameters are obtained by applying correlation analysis on temporal fluctuations of the number of particles with respect to a detection area of the digital picture, and that a time correlation function of functions is/are calculated based on the temporal fluctuations of the number of particles, and a means for displaying the calculations results.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 7, 2009
From: RIGLER, RUDOLF
To: BIOPHOS AG
Reel/Frame 023074/0726 →
Continuity (2)
Provisional Application 60831227 · Jul 17, 2006
Related Publication 20090238423A1 · Sep 24, 2009