Radiation sensor arrays for use with brachytherapy
A radiation sensor array is carried on a flexible sheet of film, for placement on the skin of a patient adjacent to a brachytherapy location beneath the skin. With the array approximately centered on a position where radiation source to skin distance is estimated to be minimum, the array of sensors is used to monitor radiation dose received at the skin. With a controller connected to the array and preferably also to the radiation source in the applicator, the radiation dose received at all skin points of interest can be monitored, a point of maximum dose and a projected approach to limit dose can be calculated, and in response the system can warn the operator or control a brachytherapy procedure so as to discontinue radiation or control the radiation level or source position in real time. The system can also include percutaneous sensors.
1 . A system for sensing radiation received at the skin surface during brachytherapy, comprising:
an array of radiation sensors carried on a flexible sheet of material adapted for placement on the skin of a patient adjacent to a brachytherapy location beneath the skin,
the array being large enough in area to cover any anticipated maximum skin dose point during a brachytherapy procedure,
a central controller separate from the radiation source with programming for control of the brachytherapy procedure,
communication means connecting the radiation sensors to the central controller,
whereby the sensors receive radiation from a radiation source in a brachytherapy procedure, and the dose received at each sensor can be communicated to the controller and monitored by the controller, which can calculate a point of maximum dose at the skin and can provide a warning if dose is projected to exceed a dose limit, or which can apply real time control to the brachytherapy radiation procedure, or which can generate a permanent record of treatment actually delivered.
2 . The system of claim 1 , wherein the flexible sheet comprises a polymeric film.
3 . The system of claim 1 , wherein the flexible sheet comprises a flexible circuit film.
4 . The system of claim 1 , wherein the communication means comprises wires secured to the flexible sheet, leading to the central controller.
5 . The system of claim 1 , wherein the system senses radiation dose at percutaneous locations as well as at the skin surface, and wherein the array further includes radiation sensors configured for placement percutaneously in a patient.
6 . The system of claim 5 , wherein the radiation sensors configured for placement percutaneously comprise sensors on the ends of needles.
7 . The system of claim 1 , wherein the flexible sheet has pressure-sensitive adhesive on a side of the sheet intended to contact a patient's skin, with a removable release covering on the adhesive for stripping prior to applying the sheet to a patient.
8 . The system of claim 1 , wherein the sensors are MOSFET sensors.
9 . The system of claim 1 , wherein the position of each sensor on the flexible sheet is partially radio-opaque, as an aid in imaging the location of the sensors relative to patient tissue.
10 . A method for sensing radiation received at the skin surface during brachytherapy and for avoiding damage to the skin, comprising:
planning a brachytherapy procedure, including a site within a patient's body for placing a radiation source carried by an applicator, and estimating an approximate position on the skin where distance from the radiation source to the skin will be a minimum distance,
placing on the patient's skin, at a position so as to be directly over the approximate position of minimum distance, an array of radiation sensors carried on a flexible sheet of material,
providing a connection of the array of radiation sensors to a central controller separate from the radiation source and with programming for control of the brachytherapy procedure,
commencing brachytherapy with the applicator at the site,
as the brachytherapy proceeds, monitoring skin radiation dose received at each of the sensors and calculating dose received at many points along the sheet of material, including non-sensor positions calculated interpolation from dose readings taken at the sensors, and predicting any point of the skin which will reach or exceed a limit dose, and
if a point of the skin is predicted to receive a limit dose of radiation, doing one of the following:
(a) sending out a warning signal;
(b) controlling the brachytherapy by shutting off the radiation source to discontinue radiation;
(c) controlling the brachytherapy in real time by modifying the level of radiation emitted from the source or the position of the source.
11 . The method of claim 10 , wherein the flexible sheet of material with the array of sensors includes, on a side intended to contact the skin, a layer of pressure sensitive adhesive, with a removable release covering on the adhesive, and the method including removing the release covering prior to applying the flexible sheet to the patient.
12 . The method of claim 10 , the method further including sensing radiation received percutaneously during the brachytherapy, and further including placing percutaneous radiation sensors beneath the skin, carried on needles, to sense radiation in the vicinity of percutaneous tissues that could be at risk, and the monitoring step further including monitoring radiation dose received at the percutaneously-placed sensors and predicting any point of percutaneous tissue that will reach or exceed a limit dose.