Derivatives of imidazo[1,2-

1. A compound of formula (I):

wherein:

X is phenyl optionally substituted by one or more groups chosen, independently of one another, from the group consisting of halogen, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkyl, (C 3 -C 7 )cycloalkyl(C 1 -C 6 )alkyl, (C 3 -C 7 )cycloalkyl(C 1 -C 6 )alkoxy, and NRaRb;

R 1 is hydrogen, halogen, (C 1 -C 6 )alkoxy, (C 1 -C 6 )alkyl, (C 3 -C 7 )cycloalkyl(C 1 -C 6 )alkyl, (C 3 -C 7 )cycloalkyl(C 1 -C 6 )alkoxy, amino or NRcRd, wherein the alkyl and alkoxy groups are optionally substituted by one or more halogen, hydroxyl, amino, or (C 1 -C 6 )alkoxy;

R 2 is hydrogen,

(C 1 -C 6 )alkyl optionally substituted by one or more groups chosen, independently of one another, from the group consisting of hydroxyl, halogen, amino, NRaRb and phenyl,

(C 1 -C 6 )alkoxy optionally substituted by one or more groups chosen, independently of one another, from the group consisting of hydroxyl, halogen, amino, and NRaRb,

(C 3 -C 7 )cycloalkyl(C 1 -C 6 )alkyl,

(C 3 -C 7 )cycloalkyl(C 1 -C 6 )alkoxy,

(C 2 -C 6 )alkenyl,

(C 2 -C 6 )alkynyl,

—CO—R 5 ,

—CO—NR 6 R 7 ,

—CO—O—R 8 ,

—NR 9 —CO—R 10 ,

NR 11 R 12 ,

halogen,

cyano, or

phenyl optionally substituted by one or more groups chosen, independently of one another, from the group consisting of halogen, (C 1 -C 6 )alkoxy, NRaRb, —CO—R 5 , —CO—NR 6 R 7 , —CO—O—R 8 , (C 3 -C 7 )-cycloalkyl(C 1 -C 6 )alkyl, (C 3 -C 7 )cycloalkyl(C 1 -C 6 )alkoxy, and (C 1 -C 6 )alkyl optionally substituted by one or more hydroxyl or NRaRb;

R 3 is hydrogen, (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy or halogen;

R 4 is hydrogen, (C 1 -C 4 )alkyl, (C 1 -C 4 )alkoxy or fluorine;

R 5 is hydrogen, phenyl or (C 1 -C 6 )alkyl;

R 6 and R 7 are independently hydrogen or (C 1 -C 6 )alkyl, or

R 6 and R 7 , taken together with the nitrogen atom to which they are attached, form a 4- to 7-membered ring optionally including another heteroatom chosen from the group consisting of N, O and S;

R 8 is (C 1 -C 6 )alkyl;

R 9 and R 10 are independently hydrogen or (C 1 -C 6 )alkyl;

R 11 and R 12 are independently (C 1 -C 6 )alkyl, or

R 11 and R 12 , taken together with the nitrogen atom to which they are attached, form a 4- to 7-membered ring optionally including another heteroatom chosen from the group consisting of N, O and S;

Ra and Rb are independently hydrogen or (C 1 -C 6 )alkyl, or

Ra and Rb, taken together with the nitrogen atom to which they are attached, form a 4- to 7-membered ring;

Rc is hydrogen; and

Rd is (C 1 -C 6 )alkyl;

provided that:

at least one of R 1 , R 2 , R 3 and R 4 is other than hydrogen,

when R 3 is methyl, then X is unsubstituted,

when R 1 is methyl, then X is unsubstituted, and

when R 2 is chlorine, then X is not a para-fluorophenyl;

or an addition salt with an acid thereof.

2. The compound according to claim 1 , wherein X is phenyl, or an addition salt with an acid thereof.

3. The compound according to claim 1 , wherein R 1 , R 3 and R 4 are hydrogen, or an addition salt with an acid thereof.

4. The compound according to claim 1 , which is:

6-Chloro-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

8-Methyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(Dimethylamino)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(1-Hydroxy-1-methylethyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

N-(4-Fluorophenyl)-6-isopropenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Chloro-N-(2-chlorophenyl)imidazo[1,2-a]pyridine-2-carboxamide,

N,6-Diphenylimidazo[1,2-a]pyridine-2-carboxamide,

N-Phenyl-6-vinylimidazo[1,2-a]pyridine-2-carboxamide,

6-Ethyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Formyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Ethynyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-[3-(1-Hydroxy-1-methylethyl)phenyl]-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-[Hydroxy(phenyl)methyl]-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Acetyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide hydrochloride (1:1),

6-Isopropyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(1-Hydroxyethyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Acetamido-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(Dimethylamino)-5-methyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Methyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

5-Methyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

7-Methyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Bromo-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Fluoro-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6,8-Difluoro-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Bromo-5-methyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Iodo-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Cyano-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(Hydroxymethyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Methoxy-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

N-(4-fluorophenyl)-6-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridine-2-carboxamide,

6-Benzoyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Isopropenyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Chloro-N-(3-fluorophenyl)imidazo[1,2-a]pyridine-2-carboxamide,

6-Chloro-N-(3-chlorophenyl)imidazo[1,2-a]pyridine-2-carboxamide,

6-Chloro-N-(3-methoxyphenyl)imidazo[1,2-a]pyridine-2-carboxamide,

6-Chloro-N-[4-(dimethylamino)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

6-Chloro-N-(4-chlorophenyl)imidazo[1,2-a]pyridine-2-carboxamide,

6-[2-(Hydroxymethyl)phenyl]-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-[3-(Hydroxymethyl)phenyl]-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-[4-(Hydroxymethyl)phenyl]-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(2-Formylphenyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(3-Formylphenyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

5,6-Dimethyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

Methyl 3-[2-(anilinocarbonyl)imidazo[1,2-a]pyridin-6-yl]benzoate,

6-(3-Acetylphenyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(3-Fluorophenyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(4-Methylphenyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(3-Methoxyphenyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-[3-(Aminomethyl)phenyl]-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(3-Chlorophenyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(3-Carbamoylphenyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-[3-(1-Hydroxyethyl)phenyl]-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(3-Methylphenyl)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(Diethylamino)-N-phenylimidazo[1,2-a]pyridine-2-carboxamide or its hydrochloride (1:1),

6-[3-(Methylcarbamoyl)phenyl]-N-phenylimidazo[1,2-a]pyridine-2-carboxamide or its hydrochloride (1:1),

6-Carbamoyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-(Dimethylamino)-N-(3-fluorophenyl)imidazo[1,2-a]pyridine-2-carboxamide,

N-(2,5-Difluorophenyl)-6-(dimethylamino)imidazo[1,2-a]pyridine-2-carboxamide,

N-(2,3-Difluorophenyl)-6-(dimethylamino)imidazo[1,2-a]pyridine-2-carboxamide,

6-(Dimethylamino)-N-(2-fluorophenyl)imidazo[1,2-a]pyridine-2-carboxamide,

N-(3-Fluorophenyl)-6-[3-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

N-(3,5-Difluorophenyl)-6-[3-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

N-(2-Chlorophenyl)-6-[3-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

6-[3-(Hydroxymethyl)phenyl]-N-(3-methylphenyl)imidazo[1,2-a]pyridine-2-carboxamide,

N-(2,5-Difluorophenyl)-6-[3-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

N-(2,3-Difluorophenyl)-6-[3-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

N-(2-Fluorophenyl)-6-[3-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

N-(5-Chloro-2-fluorophenyl)-6-[3-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

6-Morpholin-4-yl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide or its hydrochloride (1:1),

6-Azetidin-1-yl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

6-Iodo-5-methyl-N-phenylimidazo[1,2-a]pyridine-2-carboxamide,

N-(3,5-Difluorophenyl)-6-iodoimidazo[1,2-a]pyridine-2-carboxamide,

N-(3-Chlorophenyl)-6-[3-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

N-(3,5-Difluorophenyl)-6-(dimethylamino)imidazo[1,2-a]pyridine-2-carboxamide,

N-(2-Chlorophenyl)-6-(dimethylamino)imidazo[1,2-a]pyridine-2-carboxamide,

6-(Dimethylamino)-N-[3-(trifluoromethoxy)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

N-(3-Chloro-2-fluorophenyl)-6-[3-(hydroxymethyl)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

6-(Dimethylamino)-N-(3-methylphenyl)imidazo[1,2-a]pyridine-2-carboxamide,

N-(3-Chlorophenyl)-6-(dimethylamino)imidazo[1,2-a]pyridine-2-carboxamide,

N-(5-Chloro-2-fluorophenyl)-6-(dimethylamino)imidazo[1,2-a]pyridine-2-carboxamide,

N-(3-Chloro-2-fluorophenyl)-6-(dimethylamino)imidazo[1,2-a]pyridine-2-carboxamide,

N-[3-(Difluoromethoxy)phenyl]-6-(dimethylamino)imidazo[1,2-a]pyridine-2-carboxamide, or

6-(Dimethylamino)-N-[3-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridine-2-carboxamide,

or an addition salt with an acid thereof.

5. A pharmaceutical composition comprising the compound according to claim 1 or a pharmaceutically acceptable salt thereof, in combination with at least one pharmaceutically acceptable excipient.

6. A pharmaceutical composition comprising the compound according to claim 2 or a pharmaceutically acceptable salt thereof, in combination with at least one pharmaceutically acceptable excipient.

7. A pharmaceutical composition comprising the compound according to claim 3 or a pharmaceutically acceptable salt thereof, in combination with at least one pharmaceutically acceptable excipient.

8. A pharmaceutical composition comprising the compound according to claim 4 or a pharmaceutically acceptable salt thereof, in combination with at least one pharmaceutically acceptable excipient.