IP Library Granted Patent US 8,642,660
Granted Patent B2
US 8,642,660 · App. 12/341,615 · Granted Feb 4, 2014

Method for altering the lifespan of eukaryotic organisms

Inventor: David Scott Goldfarb (Mendon, NY)
Assignee: The University of Rochester
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Quick Facts
Patent No.
US 8,642,660
App. No.
12/341,615
Granted
Feb 4, 2014
Kind
B2
Abstract

A method for altering the lifespan of a eukaryotic organism. The method comprises the steps of providing a lifespan altering compound, and administering an effective amount of the compound to a eukaryotic organism, such that the lifespan of the organism is altered. In one embodiment, the compound is identified using the DeaD assay.

Claims (4)

1. A method for altering the lifespan of a eukaryotic organism comprising the steps of:

a) providing a lifespan altering compound comprising scaffold c1:

wherein the compound has an EC50 in a DeaD assay of 10 μM r less if tested in a DeaD assay; and

b) administering an effective amount of the compound to a eukaryotic organism, such that the lifespan of the eukaryotic organism is altered, wherein the altered lifespan comprises an increase in lifespan.

Assignments (2)
CONFIRMATORY LICENSE Recorded May 14, 2010
From: UNIVERSITY OF ROCHESTER
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 024386/0210 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 4, 2009
From: GOLDFARB, DAVID SCOTT
To: THE UNIVERSITY OF ROCHESTER
Reel/Frame 022205/0921 →
Continuity (3)
Provisional Application 61016362 · Dec 21, 2007
Provisional Application 61023801 · Jan 25, 2008
Related Publication 20090163545A1 · Jun 25, 2009