Dietary compositions and related methods of use
The present invention provides dietary compositions for mammalian consumption. In particular, the present invention provides compositions comprising pectin, a component comprising electrolytes, thickening agents, a sweetening agent, and water, and methods for making such compositions. In some embodiments, the dietary compositions are used for preventing and/or treating malabsorption dysfunction and associated disorders (e.g., short bowel syndrome, Crohn's disease). In some embodiments, the dietary compositions are used for preventing and/or treating colonic disorders (e.g., ulcerative colitis). The dietary compositions further find use in subjects with diarrhea, regardless of cause, subject suffering from gastric dumping syndrome, and obese patients or patients seeking to lose weight, as the composition delays gastric emptying (e.g., creating feeling of early satiety). In some embodiments, the dietary composition is a prebiotic food supplement.
1. A dietary composition comprising 2-4% by weight pectin, 2-5% by weight thickening agent, 0.5-4% by weight electrolyte component, and water, wherein the dietary composition is a pudding.
2. The dietary composition of claim 1 , wherein said dietary composition is prepared as a nutraceutical composition, a food product, or a prebiotic food supplement.
3. The dietary composition of claim 1 , wherein said dietary composition is prepared for oral consumption by a human subject.
4. The dietary composition of claim 1 , wherein said dietary composition is configured to treat malabsorption dysfunction and/or a colonic disorder in a subject.
5. The dietary composition of claim 1 , wherein said dietary composition increases intestinal transit time in said subject.
6. The dietary composition of claim 1 , wherein said dietary composition decreases gastric emptying.
7. The dietary composition of claim 1 , wherein said dietary composition increases intestinal energy absorption and/or increases intestinal fluid absorption.
8. The dietary composition of claim 1 , wherein said dietary composition treats colonic ulcerations and/or colonic mucosal injury.
9. The dietary composition of claim 1 , wherein said electrolyte component is 70 mEq sodium, 20 mEq potassium, 60 mEq chloride and 30 mEq citrate.
10. The dietary composition of claim 1 , wherein said thickening agent is gelatin.
11. The dietary composition of claim 1 , wherein said thickening agent is pudding mix.
12. The dietary composition of claim 1 , wherein said dietary composition further comprises a sweetening agent.
13. A method for treating a subject, comprising administering the composition of claim 1 to a subject.
14. The method of claim 13 , wherein the subject is human.
15. The method of claim 13 , wherein the subject has a malabsorption dysfunction.
16. The method of claim 15 , wherein the malabsorption dysfunction is selected from the group consisting of Crohn's disease and short bowel syndrome.
17. The method of claim 13 , wherein the subject has a colonic disorder.
18. The method of claim 16 , wherein said colonic disorder is ulcerative colitis.
19. A method of manufacturing the dietary composition of claim 1 , comprising mixing pectin, thickening agent, and an electrolyte component with boiling water, and cooling said mixture.
20. The method of claim 19 , wherein said cooled mixture consists of approximately 3% by weight thickening agent, 2.5% by weight pectin, 2% by weight electrolyte component, and 92.5% by weight water.