IP Library Granted Patent US 8,642,318
Granted Patent B2
US 8,642,318 · App. 12/375,097 · Granted Feb 4, 2014

Anti-fatty liver agent

Inventors: Hiroshi Kawakami (Saitama, JP); Hiroaki Matsuyama (Saitama, JP); Masao Sato (Fukuoka, JP); Katsumi Imaizumi (Fukuoka, JP)
Assignee: Megmilk Snow Brand Co., Ltd.
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Quick Facts
Patent No.
US 8,642,318
App. No.
12/375,097
Granted
Feb 4, 2014
Kind
B2
Abstract

Disclosed is an anti-fatty liver agent comprising a cell and/or a culture obtained by culturing a lactic acid bacterium belonging to Lactobacillus gasseri as an active ingredient. Also disclosed is a pharmaceutical agent having an anti-fatty liver activity or an anti-fatty liver beverage/food comprising a cell and/or a culture obtained by culturing a lactic acid bacterium belonging to Lactobacillus gasseri as an active ingredient.

Claims (11)

1. A method of treating fatty liver in a subject in need thereof, comprising administering to the subject an effective amount of Lactobacillus gasseri culture.

2. The method of claim 1 , comprising administering to the subject a food or beverage comprising the Lactobacillus gasseri culture.

3. The method of claim 1 , wherein the Lactobacillus gasseri is any one of Lactobacillus gasseri SBT2055 (FERM P-15535), and, Lactobacillus gasseri SBT0274 (FERM P-17784).

4. The method of claim 1 , wherein the Lactobacillus gasseri culture is administered to the subject orally.

5. The method of claim 1 , wherein the effective amount of Lactobacillus gasseri culture administered to the subject is 0.5 to 50 g dry weight per day.

6. The method of claim 2 , wherein the food or beverage is a yogurt fermented by Lactobacillus gasseri.

7. A method for reducing triglyceride levels in the liver of a subject having fatty liver disease, comprising administering to the subject an effective amount of Lactobacillus gasseri culture comprising Lactobacillus gasseri SBT2055 (FERM P-15535.

8. A method for reducing the amount of liver fat in a subject having fatty liver disease, comprising administering to the subject an effective amount of Lactobacillus gasseri culture comprising Lactobacillus gasseri SBT2055 (FERM P-15535.

9. The method of claim 7 , wherein the L. gasseri SBT2055 culture is a milk culture and the effective amount administered is 0.5 to 50 g dry weight per day.

10. The method of claim 8 , wherein the L. gasseri SBT2055 culture is a milk culture and the effective amount administered is 0.5 to 50 g dry weight per day.

11. The method of claim 1 , wherein the L. gasseri culture is a milk culture.

Assignments (2)
MERGER Recorded Aug 4, 2011
From: SNOW MILK BRAND CO., LTD.
To: MEGMILK SNOW BRAND CO., LTD
Reel/Frame 026698/0750 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 14, 2011
From: KAWAKAMI, HIROSHI; MATSUYAMA, HIROAKI; SATO, MASAO; IMAIZUMI, KATSUMI
To: SNOW BRAND MILK PRODUCTS CO., LTD.
Reel/Frame 025944/0835 →
Priority Claims (1)
JP 2006-201733 · Jul 25, 2006 · national
Continuity (1)
Related Publication 20100129333A1 · May 27, 2010