TRAUMA THERAPY
The invention provides a method of reducing injury to cells, tissues or organs of a body following trauma by administering a composition to the body following trauma, including: (i) a potassium channel opener or agonist and/or an adenosine receptor agonist; and (ii) a local anaesthetic. Also provided is a composition for reducing injury to cells, tissues or organs of a body following trauma including: (i) and (ii). The composition may be hypertonic.
1 . A method of reducing injury to cells, tissues or organs of a body following trauma by administering a composition to the body following trauma, including:
(i) a potassium channel opener or agonist and/or an adenosine receptor agonist; and
(ii) a local anaesthetic.
2 . A method according to claim 1 wherein a further composition including (i) and (ii) is administered following administration of the composition.
3 . A method according to claim 1 wherein the composition further includes divalent magnesium cations.
4 . A method according to claim 3 wherein the concentration of magnesium is up to about 2.5 mM.
5 . A method according to claim 1 wherein the composition is hypertonic.
6 . A composition for reducing injury to cells, tissues or organs of a body following trauma including:
(i) a potassium channel opener or agonist and/or an adenosine receptor agonist; and
(ii) a local anaesthetic.
7 . A composition according to claim 6 , further including divalent magnesium cations.
8 . A composition according to claim 6 which is hypertonic.
9 . A method of treating a trauma victim by administering a composition, including: (i) a potassium channel opener or agonist and/or an adenosine receptor agonist; and (ii) a local anaesthetic.
10 . A method of treating a trauma victim by administering a composition according to claim 6 .
11 . A composition according to claim 7 , wherein the concentration of magnesium is up to about 2.5 mM.