Method of detecting endometriosis in human subjects using SEQ ID No. 9 or an epitope thereof
A method for diagnosing endometriosis in a human subject comprising the steps of detecting a test amount of an antibody that specifically binds to SEQ ID NO:9 polypeptide or a truncated peptide comprising an epitope of SEQ ID NO: 9, in a sample from the subject; and comparing the test amount with a normal range of the antibody in a control sample from a subject who does not suffer from endometriosis, whereby a test amount above the normal range provides a positive indication in the diagnosis of endometriosis.
1. A method for diagnosing endometriosis in a human subject comprising the steps of:
(a) detecting a test amount of an antibody that specifically binds to SEQ ID NO:9 polypeptide or a truncated peptide comprising an epitope of SEQ ID NO: 9, in a sample from the subject; and
(b) comparing the test amount with a normal range of the antibody in a control sample from a subject who does not suffer from endometriosis, whereby a test amount above the normal range provides a positive indication in the diagnosis of endometriosis.
2. The method of claim 1 , wherein the sample comprises blood serum.
3. The method of claim 1 or 2 , wherein the step of detecting comprises capturing the antibody from the sample with an immobilized peptide where said peptide is SEQ ID NO: 9 or a peptide comprising an epitope of SEQ ID NO: 9 and detecting captured antibody.
4. The method of claim 1 wherein said polypeptide has amino acid sequences identical to SEQ ID NO: 9.
5. The method of claim 1 wherein said peptide is a truncated peptide comprising an epitope of SEQ ID NO: 9.
6. The method of claim 1 wherein said SEQ ID NO: 9 polypeptide is produced by recombinant means.
7. The method of claim 1 wherein said truncated peptide of SEQ ID NO: 9 is produced by recombinant means.