Granted Patent
B2
US 8,273,856 · App. 12/466,565 · Granted Sep 25, 2012
Purified linear epitopes from cashew nuts, nucleic acids encoding therefor and associated methods
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Abstract
Disclosed are major allergenic proteins in cashew nut, which are legumin-like proteins and 2S albumins. Also disclosed is a polypeptide allergen in the 7S superfamily, which includes vicilin-like and sucrose binding proteins. Several linear epitopes of the cashew nut are identified and characterized. The invention further discloses the sequence of cDNA encoding the allergenic polypeptide, the allergen being designated Ana o 1, and also describes the characterization of the expressed recombinant polypeptide and associated methods employing the polypeptide.
Claims (1)
1. A purified Ig-E binding immunogenic polypeptide the amino acid sequence of which is selected from the group consisting of SEQ ID NOs: 3 and 8.
Assignments (3)
CONFIRMATORY LICENSE
Recorded Jul 24, 2017
From: FLORIDA STATE UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 043077/0554 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 1, 2015
From: ROUX, KENNETH; SATHE, SHRIDHAR
To: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION
Reel/Frame 037174/0876 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 1, 2015
From: TEUBER, SUZANNE S.
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 037175/0011 →
Continuity (5)
Provisional Application
60326793
· Oct 3, 2001
Provisional Application
60371774
· Apr 11, 2002