IP Library Granted Patent US 8,318,482
Granted Patent B2
US 8,318,482 · App. 12/480,635 · Granted Nov 27, 2012

VCP-based vectors for algal cell transformation

Assignee: Aurora Algae, Inc.
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Quick Facts
Patent No.
US 8,318,482
App. No.
12/480,635
Granted
Nov 27, 2012
Kind
B2
Abstract

Provided herein are exemplary vectors for transforming algal cells. In exemplary embodiments, the vector comprises a Violaxanthin-chlorophyll a binding protein (Vcp) promoter driving expression of an antibiotic resistance gene in an algal cell. Embodiments of the invention may be used to introduce a gene (or genes) into the alga Nannochloropsis , such that the gene(s) are expressed and functional. This unprecedented ability to transform Nannochloropsis with high efficiency makes possible new developments in phycology, aquaculture and biofuels applications.

Claims (6)

1. An expression vector for algal cell transformation comprising the nucleotide sequence of SEQ ID NO:1.

2. The expression vector of claim 1 , wherein a promoter in the expression vector modulates the expression of a gene governed by the promoter in response to light intensity.

3. The expression vector of claim 2 , wherein the promoter in the expression vector increases the expression of the gene governed by the promoter in response to a decrease in light intensity.

4. The expression vector of claim 2 , wherein the promoter is a Vcp promoter.

5. The expression vector of claim 1 , wherein the algal cell is of algal genus Nannochloropsis.

6. The expression vector of claim 1 , wherein the expression vector is at least partially expressed as part of a transformed algal cell.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Apr 20, 2015
From: SILICON VALLEY BANK, AS AGENT
To: AURORA ALGAE, INC.
Reel/Frame 035452/0305 →
SECURITY INTEREST Recorded Nov 8, 2011
From: AURORA ALGAE, INC.
To: SILICON VALLEY BANK
Reel/Frame 027249/0001 →
CHANGE OF NAME Recorded Aug 26, 2011
From: AURORA BIOFUELS, INC.
To: AURORA ALGAE, INC.
Reel/Frame 026817/0720 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 14, 2009
From: KILIAN, OLIVER; VICK, BERTRAND
To: AURORA BIOFUELS, INC.
Reel/Frame 023372/0607 →
Continuity (2)
Provisional Application 61059672 · Jun 6, 2008
Related Publication 20090317904A1 · Dec 24, 2009