2-propynyl adenosine analogs with modified 5′-ribose groups having A2A agonist activity
The invention provides compounds having the following general formula (I): wherein X, R 1 , R 2 , R 7 and Z are as described herein.
1. A composition comprising a compound of formula
or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
2. A composition a compound of the formula
or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
3. A composition comprising a compound of formula
or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
4. A composition comprising a compound of formula
or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
5. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
6. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
7. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
8. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
9. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
10. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
11. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
12. A composition comprising a compound of formula
or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
13. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
14. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
15. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
16. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
17. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
18. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
19. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.
20. A composition comprising a compound of formula
or a stereoisomer or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.