Mast cell stabilizers to prevent or treat laminitis
Provided herein are mast cell stabilizers used to prevent, treat, or mitigate severity of laminitis. Mast cell stabilizers can be combined with antihistamines and other medicaments to prevent, treat, or mitigate severity of laminitis.
1. A method for the treatment of laminitis, the method comprising administering cromolyn sodium to a horse in need thereof, wherein the cromolyn sodium is administered through an intravenous injection in a dose of between about 0.5 and about 10 mg/kg of the horse's body weight and wherein the cromolyn sodium treats laminitis in the horse.
2. The method of claim 1 , wherein the horse suffers from acute laminitis and has one or more affected sites and wherein the cromolyn sodium is administered directly to each of the one or more affected sites.
3. The method of claim 1 , wherein the horse suffers from acute laminitis and wherein the cromolyn sodium is administered in a single dose.
4. The method of claim 1 , the method further comprising administering another intravenous dose of cromolyn sodium to the horse within about 3 to 4 days after administering a first dose.
5. A method for the treatment of laminitis, the method comprising administering nedocromil sodium to a horse in need thereof, wherein the nedocromil sodium is administered through an intravenous injection in a dose of between about 0.5 and 10 mg/kg of the horse's body weight and wherein the nedocromil treats laminitis in the horse.
6. The method of claim 5 , wherein the horse suffers from acute laminitis and has one or more affected sites and wherein the nedocromil sodium is administered directly to the each of the one or more affected sites.
7. The method of claim 5 , wherein the horse suffers from acute laminitis and wherein the nedocromil sodium is administered in a single dose.
8. The method of claim 5 , the method further comprising administering another intravenous dose of cromolyn sodium to the horse within about 3 to 4 days after administering a first dose.
9. The method of claim 1 , wherein the dose is between about 1 and 7 mg/kg of the horse's body weight.
10. The method of claim 5 , wherein the dose is between about 1 and 7 mg/kg of the horse's body weight.
11. The method of claim 1 , where the horse suffers from chronic laminitis and wherein the cromolyn sodium is administered at least once a week.
12. The method of claim 5 , where the horse suffers from chronic laminitis and wherein the nedocromil sodium is administered at least once a week.
13. The method of claim 1 wherein the dose is administered through an intravenous injection into the horse's one or more affected legs.
14. The method of claim 5 wherein the dose is administered through an intravenous injection into the horse's one or more affected legs.
15. The method of claim 13 wherein the intravenous injection is into a digital vein of the one or more affected legs.
16. The method of claim 14 wherein the intravenous injection is into a digital vein of the one or more affected legs.