USE OF QUINOLINE DERIVATIVES IN THE TREATMENT OF PAIN AND IRRITABLE BOWEL SYNDROME
The use of 5-HT 6 serotonin receptor antagonists of formula (I): or pharmaceutically acceptable salts thereof, is described for the treatment of Irritable Bowel Syndrome and pain in mammals, more particularly inflammatory, neuropathic or visceral pain.
1 - 8 . (canceled)
9 . A method of treatment of pain in humans, which method comprises the administration to a human in need of such treatment, an effective amount of a compound of formula (I), or a pharmaceutically acceptable salt thereof:
wherein:
R 1 represents a halogen atom; and
n represents 0, 1, 2 or 3.
10 . A method of treatment according to claim 9 , wherein the pain is inflammatory pain.
11 . A method of treatment according to claim 9 , wherein the pain is visceral pain.
12 . A method of treatment according to claim 9 , wherein the pain is neuropathic pain.
13 . A method of treatment of irritable bowel syndrome in humans, which method comprises the administration to a human in need of such treatment, an effective amount of a compound of formula (I) as defined in claim 9 , or a pharmaceutically acceptable salt thereof.
14 . A method of treatment of irritable bowel syndrome in humans according to claim 13 , wherein the human is female.
15 - 20 . (canceled)