Granted Patent
B2
US 7,993,658 · App. 12/546,368 · Granted Aug 9, 2011
Targeting of triacylclycerol synthase gene for tuberculosis treatment
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Abstract
Disclosed herein are novel methods for screening for compounds useful in treating or preventing tuberculosis. In exemplary embodiments, screening methods are based on the implementation or manipulation of triacylglycerol synthase like polypeptides or polynucleotides encoding the same. The methods are useful in identifying agents active against TB infection.
Claims (1)
1. An agent which regulates the activity of a Mycobacterium tuberculosis triacylglycerol storage (MTTGS) polypeptide, said agent being an RNA molecule, an antisense oligonucleotide, or a ribozyme that targets a nucleic acid sequence encoding SEQ ID NO. 2.
Assignments (1)
CONFIRMATORY LICENSE
Recorded Apr 8, 2015
From: UNIVERSITY OF CENTRAL FLORIDA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 035387/0115 →
Continuity (3)
Provisional Application
60748283
· Dec 7, 2005