IP Library Granted Patent US 8,283,924
Granted Patent B2
US 8,283,924 · App. 12/582,409 · Granted Oct 9, 2012

Eddy-current artifact reduction in balanced steady-state free precession magnetic resonance imaging

Assignee: University of Southern California
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Quick Facts
Patent No.
US 8,283,924
App. No.
12/582,409
Granted
Oct 9, 2012
Kind
B2
Abstract

Magnetic resonance imaging techniques are described that utilize bSSFP sequences in which two or more gradient waveforms are interleaved in a “groupwise” fashion, i.e., each waveform is executed consecutively two or more times before switching to the other waveform, where “N” counts the number of times each waveform is executed consecutively. As a result, embodiments of the present disclosure can mitigate steady-state signal distortions or artifacts in interleaved balanced steady-state free precession (bSSFP) caused by slightly unbalanced eddy-current fields. Related MRI systems are also described.

Claims (27)

1. A method of artifact reduction using gradient waveform grouping for balanced SSFP imaging, the method comprising:

with a MRI system, providing a balanced steady state free precession (SSFP) pulse sequence of RF pulses and balanced gradient pulses to an object;

interleaving two different gradient waveforms of the SSFP pulse sequence;

switching between from a first of the two different gradient waveforms to the second gradient waveform after a number of N repetitions, where N>2; and

imaging the object with the MRI system.

2. The method of claim 1 , wherein the repetition time (TR) is 8.0 ms.

3. The method of claim 1 , wherein providing a balanced steady state free precession pulse sequence comprises providing a plurality of phase encoding steps, wherein each phase encoding step comprises a slice selection gracient, a phase encoding gradient, and a readout gradient.

4. The method of claim 1 , wherein a flip angle is 40°.

5. The method of claim 4 , wherein 180° phase cycling occurs every TR.

6. The method of claim 1 , wherein N=4.

7. The method of claim 1 , wherein N=6.

8. The method of claim 1 , wherein imaging an object comprises CINE imaging.

9. The method of claim 8 , wherein the SSFP pulse sequence comprises a single-slice 2DFT pulse sequence.

10. The method of claim 8 , wherein the flip angle is about 50°.

11. The method of claim 1 , wherein a velocity-encoding value (VENC) is about 4.6 m/s.

12. The method of claim 1 , wherein imaging the object comprises transient imaging.

13. A MRI system for generating MRI images of an object, the MRI system comprising:

a static field generator configured to generate a static magnetic field B 0 ;

a gradient field generator configured to generate a time-varying gradient field G(r), parallel to B 0 ; and

an RF excitation pulse generator configured to generate an RF excitation field B 1 and apply the field B 1 to the object so that nuclear spins in the object flip at a flip angle; and

a balanced SSFP pulse sequence of RF and gradient pulses, wherein the SSFP pulse sequence includes two interleaved different gradient waveforms that are alternated after a number of N repetitions, where N>2; and

an image processing system configured and arranged to display images of the object.

14. The system of claim 13 , wherein the SSFP pulse sequence comprises a single-slice 2DFT pulse sequence.

15. The system of claim 13 , wherein the VENC is about 4.6 m/s.

16. The system of claim 13 , wherein N=6.

17. An MRI controller system for a magnetic resonance imaging (MRI) system, the system comprising:

a controller configured and arranged to (i) control an RF excitation pulse generator and gradient field generator to produce a balanced steady state free precession (SSFP) pulse sequence, (ii) interleave two different gradient waveforms of the SSFP pulse sequence, (iii) switch between a first of the two different gradient waveforms to the second gradient waveform after a number of N repetitions, where N >2, (iv) image an object with the MRI system.

Assignments (2)
CONFIRMATORY LICENSE Recorded Dec 18, 2009
From: UNIVERSITY OF SOUTHERN CALIFORNIA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 023676/0834 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 3, 2009
From: NIELSEN, JON-FREDRIK; NAYAK, KRISHNA S.
To: UNIVERSITY OF SOUTHERN CALIFORNIA
Reel/Frame 023598/0834 →
Continuity (2)
Provisional Application 61106782 · Oct 20, 2008
Related Publication 20100102816A1 · Apr 29, 2010