Polymers functionalized with ion-specific recognition elements
Polymeric compounds containing polymer backbones functionalized with ion-specific recognition elements and methods for the use of these compounds are described herein. The polymeric compounds may contain multiple types of ion-specific recognition elements depending on a specific application. The polymeric compounds can be used to remove ionic species from a solution, for example, in separations applications in which a single or multiple types of ionic species are desired to be removed from the solution.
1. A polymeric compound comprising the following calix[4]pyrrole monomeric unit:
2. The polymeric compound of claim 1 , further comprising the following methyl methacrylate monomeric unit:
3. The polymeric compound of claim 2 , further comprising the following benzo-15-crown-5 ether monomeric unit:
4. The polymeric compound of claim 1 , wherein the polymeric compound is further functionalized with a zwitterion-specific recognition element.
5. A method of removing an ionic species from a solution comprising adding a polymeric compound comprising the following calix[4]pyrrole monomeric unit:
to the ionic species in the solution.
6. The method of claim 5 , wherein the ionic species is a cationic species.
7. The method of claim 5 , wherein the ionic species is an anionic species.
8. The method of claim 5 , wherein the ionic species is a zwitterionic species.
9. The method of claim 5 , wherein the ionic species comprises a mixture of two or more ionic species selected from cations, anions, and zwitterions.
10. The method of claim 5 , wherein the polymeric compound further comprises the following methyl methacrylate monomeric unit:
11. The method of claim 10 , wherein the polymeric compound further comprises the following benzo-15-crown-5 ether monomeric unit:
12. The method of claim 5 , wherein the polymeric compound is further functionalized with a zwitterion-specific recognition element.
13. A method of treating an ion imbalance in a subject comprising:
selecting a subject with or suspected of having an elevated level of an ion; and
administering to the subject a polymeric compound comprising the following calix[4]pyrrole monomeric unit:
14. The method of claim 13 , wherein the ion is a cation.
15. The method of claim 13 , wherein the ion is an anion.
16. The method of claim 13 , wherein the ion is a zwitterion.
17. The method of claim 13 , wherein the ion comprises a mixture of two or more ionic species selected from cations, anions, and zwitterions.
18. The method of claim 13 , wherein the polymeric compound further comprises the following methyl methacrylate monomeric unit:
19. The method of claim 18 , wherein the polymeric compound further comprises the following benzo-15-crown-5 ether monomeric unit:
20. The method of claim 13 , wherein the polymeric compound is further functionalized with a zwitterion-specific recognition element.
21. The polymeric compound of claim 1 , wherein the polymeric compound is a homopolymer of one of the following calix[4]pyrrole monomeric units:
22. The method of claim 5 , wherein the polymeric compound is a homopolymer of one of the following calix[4]pyrrole monomeric units:
23. The method of claim 13 , wherein the polymeric compound is a homopolymer of one of the following calix[4]pyrrole monomeric units: