Injectable calcium phosphate cement
The invention is related to a premixed putty calcium phosphate composition comprising at least two calcium phosphate minerals, at least one reaction retarding agent, at least one binding agent, at least one sodium phosphate, and at least one nonaqueous extender, wherein one of said at least two calcium phosphate minerals contains a stabilizing agent.
1. A kit for forming a calcium phosphate bone cement comprising:
(a) a first container comprising a premixed putty comprising stabilized di-calcium phosphate dihydrate containing from about 10 ppm to about 60 ppm of magnesium, at least one binding agent, and at least one sodium phosphate compound and
(b) a second container comprising a premixed putty comprising a second calcium phosphate mineral, at least one reaction retarding agent, at least one binding agent, and at least one nonaqueous extender.
2. A kit for forming a calcium phosphate bone cement comprising:
(a) a first container comprising a powder mixture of stabilized di-calcium phosphate dihydrate containing from about 10 ppm to about 60 ppm of magnesium, a second calcium phosphate mineral, and at least one reaction retarding agent, and
(b) a second container comprising a solvent comprising at least one binding agent, and at least one sodium phosphate compound, wherein the first container is in close proximity with a desiccant.
3. The kit of claim 2 , wherein said first container includes a moisture permeable barrier, and said first container and said desiccant are sealed in a substantially moisture impermeable package.
4. The kit of claim 2 , wherein said desiccant is silicon.
5. The kit of claim 4 , wherein the amount of silicon present is about 10 grams.
6. The kit of claim 2 , wherein said desiccant is gamma-ray radiation compatible.