Neisserial antigens
The invention provides proteins from Neisseria meningitidis (strains A & B) and from Neisseria gonorrhoeae , including amino acid sequences, the corresponding nucleotide sequences, expression data, and serological data. The proteins are useful antigens for vaccines, immunogenic compositions, and/or diagnostics.
1. An isolated protein comprising:
(a) the amino acid sequence of SEQ ID NO: 652; or
(b) an amino acid sequence having 95% or greater sequence identity to the amino acid sequence of SEQ ID NO: 652.
2. The isolated protein of claim 1 comprising (b).
3. The isolated protein of claim 2 , wherein the amino acid sequence has 99% or greater sequence identity to the amino acid sequence of SEQ ID NO: 652.
4. A composition comprising the protein of any one of claim 1 , 2 , or 3 and an adjuvant.
5. The composition of claim 4 further comprising a pharmaceutically acceptable carrier.