IP Library › Granted Patent US 8,450,345
Granted Patent B2
US 8,450,345 · App. 12/656,992 · Granted May 28, 2013

Iminosugars and methods of treating viral diseases

Inventors: Urban Ramstedt (Silver Spring, MD); Brennan Klose (Silver Spring, MD); Nicole Zitzmann (Oxford, GB); Raymond A. Dwek (Oxford, GB); Terry D. Butters (Oxford, GB)
Assignees: The Chancellor, Masters and Scholars of the University of Oxford; United Therapeutics Corporation
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Quick Facts
Patent No.
US 8,450,345
App. No.
12/656,992
Granted
May 28, 2013
Kind
B2
Abstract

Provided are methods of treating or preventing viral infections caused by or associated with a Dengue virus using iminosugars.

Claims (4)

1. A method of treating Dengue viral infection comprising administering to the subject in need thereof an effective amount of N-(9-Methoxynonyl)deoxynojirimycin or a pharmaceutically acceptable salt thereof.

2. The method of claim 1 , wherein the viral infection is caused by or associated with a Dengue 2 virus.

3. The method of claim 1 , wherein the subject is a mammal.

4. The method of claim 1 , wherein the subject is a human being.

Assignments (5)
CHANGE OF NAME Recorded Sep 8, 2016
From: UNITHER VIROLOGY, LLC
To: EMERGENT VIROLOGY LLC
Reel/Frame 039950/0898 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 23, 2015
From: UNITED THERAPEUTICS CORPORATION
To: UNITHER VIROLOGY, LLC
Reel/Frame 036869/0480 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME PREVIOUSLY RECORDED ON REEL 024361 FRAME 0112. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Dec 15, 2014
From: ZITZMANN, NICOLE; DWEK, RAYMOND A.; BUTTERS, TERRY D.
To: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Reel/Frame 034631/0284 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 10, 2010
From: ZITZMANN, NICOLE; DWEK, RAYMOND A.; BUTTERS, TERRY D.
To: UNIVERSITY OF OXFORD
Reel/Frame 024361/0112 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 10, 2010
From: RAMSTEDT, URBAN; KLOSE, BRENNAN
To: UNITED THERAPEUTICS CORPORATION
Reel/Frame 024361/0128 →
Continuity (3)
Provisional Application 61202367 · Feb 23, 2009
Provisional Application 61272255 · Sep 4, 2009
Related Publication 20100222383A1 · Sep 2, 2010