Method for treating diabetes
This application is directed to the use of steroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.
1. A compound which is
or a pharmaceutically acceptable salt thereof.
2. A compound which is
or a pharmaceutically acceptable salt thereof.
3. A compound which is
or a pharmaceutically acceptable salt thereof.
4. A compound which is
or a pharmaceutically acceptable salt thereof.
5. A pharmaceutical composition comprising the compound of claim 1 and a pharmaceutically acceptable diluent or carrier.
6. A pharmaceutical composition comprising the compound of claim 2 and a pharmaceutically acceptable diluent or carrier.
7. A pharmaceutical composition comprising the compound of claim 3 and a pharmaceutically acceptable diluent or carrier.
8. A pharmaceutical composition comprising the compound of claim 4 and a pharmaceutically acceptable diluent or carrier.