Compositions and methods of use
This invention relates to the use of plant extracts, compositions thereof, and compounds isolated from plant extracts or obtained from synthetic means thereof, for the treatment of diseases, disorders or symptoms thereof (e.g., proliferation disorders, cancer).
1. A method of treating cancer in a subject comprising administering to the subject a composition comprising an effective amount of 8-hydroxyhexadecanoic acid, or a salt thereof, thereby treating said cancer;
wherein said cancer is a lung cancer.
2. A method of treating cancer in a subject comprising administering to the subject a composition comprising an effective amount of 8-hydroxyhexadecanoic acid, or a salt thereof, thereby treating said cancer;
wherein said cancer is a lung cancer;
wherein said lung cancer is a non-small cell lung cancer.
3. A method of treating cancer in a subject comprising administering to the subject a composition comprising an effective amount of 8-hydroxyhexadecanoic acid, or a salt thereof, thereby treating said cancer;
wherein said cancer is a lung cancer;
wherein said lung cancer is mediated by HOP-92 or NCI-H460 cancer cells.
4. A method of treating cancer in a subject comprising administering to the subject a composition comprising an effective amount of 8-hydroxyhexadecanoic acid, or a salt thereof, thereby treating said cancer;
wherein said cancer is leukemia.
5. A method of treating cancer in a subject comprising administering to the subject a composition comprising an effective amount of 8-hydroxyhexadecanoic acid, or a salt thereof, thereby treating said cancer;
wherein said cancer is leukemia;
wherein said leukemia is mediated by CCRF-CEM, K-562, SR, MOLT-4, RPMI-8226, or HL-60(TB) cancer cells.