IP Library Granted Patent US 8,268,839
Granted Patent B2
US 8,268,839 · App. 12/717,349 · Granted Sep 18, 2012

Compounds

Assignee: Glaxosmithkline LLC
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Quick Facts
Patent No.
US 8,268,839
App. No.
12/717,349
Granted
Sep 18, 2012
Kind
B2
Abstract

The present invention relates to therapeutically active xanthine derivative compounds of Formula (I): corresponding processes for manufacture of said derivatives, pharmaceutical formulations containing and uses of such compounds in therapy, particularly in treatment of diseases where under-activation of the HM74A receptor contributes to the disease or where activation of the receptor will be beneficial.

Claims (3)

1. A method for treatment of type II diabetes mellitus comprising administering to a subject in need thereof a therapeutically effective amount of a compound which is 8-chloro-3-pentyl-3,7-dihydro-1H-purine-2,6-dione

a pharmaceutically acceptable salt thereof.

2. The method for treatment of type II diabetes mellitus according to claim 1 , wherein the subject is a human.

Assignments (1)
CHANGE OF NAME Recorded Mar 10, 2010
From: SMITHKLINE BEECHAM CORPORATION
To: GLAXOSMITHKLINE LLC
Reel/Frame 024055/0203 →
Priority Claims (3)
GB 0403282.7 · Feb 14, 2004 · national
GB 0423562.8 · Oct 22, 2004 · national
GB 0428375.0 · Dec 24, 2004 · national
Continuity (2)
Continuation 10589474
Related Publication 20100160354A1 · Jun 24, 2010