Aerosolized Drug Delivery System
A system for delivering an aerosolized drug to a patient includes an aerosol drug generator coupled to a mouthpiece including two sensing ports. A pressure sensor is connected to the two sensing ports of the mouthpiece. The system also includes a data processing component which calculates an inspired flow rate based on a signal from the pressure sensor, and a measurement component which measures the inhalation time, which is the time during which the aerosolized drug is inhaled at the inspired flow rate. The data processing component also calculates the amount of the aerosolized drug delivered to the patient based on the inspired flow rate, the amount of inhalation time, and a drug delivery coefficient.
1 . A system for delivering an aerosolized drug to a patient comprising:
an aerosol drug generator coupled to a mouthpiece including two sensing ports;
a pressure sensor connected to the two sensing ports;
a data processing component adapted to calculate an inspired flow rate based on a signal from the pressure sensor, and
a measurement component adapted to measure an amount of inhalation time during which an aerosolized drug is inhaled at the inspired flow rate,
wherein the data processing component is adapted to calculate an amount of the aerosolized drug delivered to the patient based on the inspired flow rate, the amount of inhalation time, and a drug delivery coefficient.
2 . The system of claim 1 , further comprising a display component adapted to display the inspired flow rate.
3 . The system of claim 2 , wherein the display component is further adapted to display a desired flow rate.
4 . The system of claim 1 , wherein the data processing component is further adapted to compare the inspired flow rate to a desired flow rate.
5 . The system of claim 1 , wherein the data processing component is further adapted to calculate a percentage of a time during which the aerosolized drug was inhaled in relation to a total time of a therapy session.
6 . The system of claim 5 , wherein the display component is further adapted to display the percentage of time.
7 . The system of claim 1 , wherein the data processing component is adapted to calculate a plurality of inspired flow rates.
8 . The system of claim 1 , wherein the mouthpiece comprises a two-way airflow valve.
9 . A system for delivering an aerosolized drug to a patient comprising:
an aerosol drug generator coupled to a mouthpiece including two sensing ports;
a pressure sensor connected to the two sensing ports; and
a signal receiving component adapted to receive signals from the pressure sensor, and a data processing component adapted to calculate a plurality of inspired flow rates based on the signals from the pressure sensor.
a display component comprising a plurality of indicator lights, wherein each of the plurality of indicator lights corresponds to an inspired flow rate of the plurality of inspired flow rates.
10 . The system of claim 9 , wherein system further comprises a display component comprising a plurality of indicator lights, wherein each of the plurality of indicator lights corresponds to an inspired flow rate of the plurality of inspired flow rates.
11 . The system of claim 9 , wherein the computer system further comprises a measurement component adapted to measure an amount of inhalation time during which the aerosolized drug is inhaled at each of the plurality of inspired flow rates.
12 . The system of claim 11 , wherein the data processing component is further adapted to calculate an amount of the aerosolized drug delivered to the patient based the plurality of inspired flow rates, the amount of inhalation time, and a drug delivery coefficient.
13 . The system of claim 9 , wherein the data processing component is further adapted to calculate a percentage of a time during which the aerosolized drug was inhaled in relation to a total time of a therapy session.
14 . The system of claim 13 , wherein the display component is further adapted to display the percentage of time.
15 . The system of claim 9 , further comprising a valve controlled in response to a predetermined pressure sensor signal, said valve controlling an air flow through said aerosol drug generator during patient expiration.
16 . A method of estimating an amount of aerosolized drug delivered to a patient during a therapy session using an aerosol generator, said method comprising:
calculating an inspired flow rate of the patient as the patient inhales an aerosolized drug through a mouthpiece by sensing a pressure differential across the mouthpiece;
measuring an amount of inhalation time during which the aerosolized drug is inhaled at the inspired flow rate; and
calculating the amount of aerosolized drug delivered to the patient based on the inspired flow rate, the amount of inhalation time, and a drug delivery coefficient.
17 . The method of claim 16 , further comprising displaying the inspired flow rate.
18 . The method of claim 17 , further comprising displaying a desired flow rate.
19 . The method of claim 16 , further comprising determining a period of patient expiration and controlling an air flow through said aerosol generator during said period.
20 . The method of claim 15 , further comprising calculating a percentage of a time during which the aerosolized drug was inhaled in relation to a total time of the therapy session.