IP Library Granted Patent US 9,168,398
Granted Patent B2
US 9,168,398 · App. 12/743,127 · Granted Oct 27, 2015

Skin treatment compositions

Inventors: Judy Hattendorf (Marina Del Ray, CA); Steve Carlson (San Mateo, CA)
Assignee: OMP, INC.
A61Q19/02A61K8/602
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Quick Facts
Patent No.
US 9,168,398
App. No.
12/743,127
Granted
Oct 27, 2015
Kind
B2
Abstract

Arbutin-containing compositions are useful for topical application to provide enhanced luminosity, brightening or lightening to the skin of a user and are at least 85% as efficacious (with regard to skin lightening, when used alone or in a system as measured by Chromameter® b* parameter values) as substantially corresponding compositions containing hydroquinone in an amount from about the same molar amount to about 1.5 times the molar amount of arbutin.

Claims (14)

1. An arbutin-containing composition comprising:

arbutin in an amount from about 5% to about 10% by weight of the total composition;

a preservative in an amount from about 0.01 to about 5% by weight of the total composition;

a chelating agent in an amount from about 0.01 to about 5% by weight of the total composition;

a humectant in an amount from about 1 to about 20% by weight of the total composition;

an emulsifier in an amount from about 1 to about 20% by weight of the total composition;

a pH adjustment agent in an amount from about 0.01 to about 5% by weight of the total composition; and

a reducing agent in an amount from about 0.1 to about 10% by weight of the total composition, wherein the composition is at least 85% as efficacious with regard to skin lightening, when used alone or in a system as measured by Chromameter® b* parameter values as a substantially corresponding composition containing hydroquinone in an amount from about the same molar amount to about 1.5 times the molar amount of arbutin.

2. The arbutin-containing composition of claim 1 comprising an oil phase comprising an emollient, a preservative and an antioxidant.

3. The arbutin-containing composition of claim 2 comprising

emollient in an amount from about 2 to about 25% by weight of the total composition;

preservative in an amount from about 0.01 to about 5% by weight based on the total composition; and

antioxidant in an amount from about 0.1 to about 2% by weight of the total composition.

4. The arbutin-containing composition of claim 1 , comprising 7% arbutin.

Assignments (20)
SECURITY INTEREST Recorded Jul 30, 2026
From: OBAGI COSMECEUTICALS LLC
To: MIDCAP FINANCIAL TRUST, AS ADMINISTRATIVE AGENT AND COLLATERAL AGENT
Reel/Frame 075464/0639 →
RELEASE OF SECURITY INTEREST Recorded Nov 17, 2025
From: TCW ASSET MANAGEMENT COMPANY LLC, AS ADMINISTRATIVE AGENT
To: OBAGI COSMECEUTICALS LLC
Reel/Frame 072928/0385 →
PATENT SECURITY AGREEMENT Recorded Nov 17, 2025
From: OBAGI COSMECEUTICALS LLC
To: LSSF II OFFSHORE INVESTMENTS, LP, AS ADMINISTRATIVE AGENT
Reel/Frame 073625/0459 →
RELEASE OF SECURITY INTEREST Recorded Apr 8, 2025
From: BARCLAYS BANK PLC, AS COLLATERAL AGENT
To: SOLTA MEDICAL, INC.; PRECISION DERMATOLOGY, INC.; BAUSCH HEALTH IRELAND LIMITED (F/K/A/ VALEANT PHARMACEUTICALS IRELAND LIMITED); SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD; SANTARUS, INC.; MEDICIS PHARMACEUTICAL CORPORATION; HUMAX PHARMACEUTICAL S.A.; SOLTA MEDICAL IRELAND LIMITED; BAUSCH & LOMB MEXICO, S.A. DE C.V.; BAUSCH+LOMB OPS B.V.; BAUSCH HEALTH AMERICAS, INC.; BAUSCH HEALTH COMPANIES INC.; BAUSCH HEALTH HOLDCO LIMITED; BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC); BAUSCH HEALTH POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (F/K/A VALEANT PHARMA POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA); BAUSCH HEALTH US, LLC; BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC.; ICN POLFA RZESZOW SPOLKA AKCYJNA (A/K/A ICN POLFA RZESZOW S.A.); ORAPHARMA, INC.; PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.); SOLTA MEDICAL DUTCH HOLDINGS B.V.; V-BAC HOLDING CORP.; VRX HOLDCO LLC; 1261229 B.C. LTD.; 1530065 B.C. LTD.
Reel/Frame 070778/0199 →
RELEASE OF SECURITY INTEREST Recorded Mar 21, 2025
From: JPMORGAN CHASE BANK, N.A.
To: OBAGI COSMECEUTICALS LLC
Reel/Frame 070592/0979 →
SECURITY INTEREST Recorded Mar 18, 2025
From: OBAGI COSMECEUTICALS LLC
To: TCW ASSET MANAGEMENT COMPANY LLC, AS ADMINISTRATIVE AGENT
Reel/Frame 070546/0595 →
SECURITY INTEREST Recorded Aug 1, 2022
From: OBAGI COSMECEUTICALS LLC
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 060690/0148 →
RELEASE OF SECURITY INTEREST Recorded Jul 29, 2022
From: TCW ASSET MANAGEMENT COMPANY LLC
To: OBAGI COSMECEUTICALS LLC
Reel/Frame 060668/0771 →
RELEASE OF SECURITY INTEREST Recorded Mar 19, 2021
From: WELLS FARGO BANK, NATIONAL ASSOCIATION
To: OBAGI COSMECEUTICALS LLC
Reel/Frame 055652/0735 →
SECURITY INTEREST Recorded Mar 16, 2021
From: OBAGI COSMECEUTICALS LLC
To: TCW ASSET MANAGEMENT COMPANY LLC, AS COLLATERAL AGENT
Reel/Frame 055613/0083 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Dec 13, 2018
From: OBAGI COSMECEUTICALS LLC
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 047873/0114 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 11, 2017
From: OMP, INC.
To: OBAGI COSMECEUTICALS LLC
Reel/Frame 044829/0244 →
RELEASE OF SECURITY INTEREST IN SPECIFIED PATENTS Recorded Nov 14, 2017
From: BANK OF NEW YORK MELLON
To: OMP, INC.
Reel/Frame 044765/0176 →
RELEASE OF SECURITY INTEREST IN SPECIFIED PATENTS Recorded Nov 14, 2017
From: BARCLAYS BANK PLC
To: OMP, INC.
Reel/Frame 044440/0037 →
SECURITY INTEREST Recorded Jul 19, 2017
From: OMP, INC.
To: THE BANK OF NEW YORK MELLON
Reel/Frame 043041/0751 →
NOTICE OF SUCCESSION OF AGENCY Recorded Jan 9, 2015
From: GOLDMAN SACHS LENDING PARTNERS, LLC
To: BARCLAYS BANK PLC, AS SUCCESSOR AGENT
Reel/Frame 034749/0689 →
SECURITY AGREEMENT Recorded Jul 29, 2013
From: OMP, INC.
To: GOLDMAN SACHS LENDING PARTNERS LLC
Reel/Frame 030919/0031 →
RELEASE OF SECURITY INTEREST Recorded May 30, 2013
From: COMERICA BANK, A TEXAS BANKING ASSOCIATION, AS AGENT
To: OBAGI MEDICAL PRODUCTS, INC.; OMP, INC.
Reel/Frame 030518/0552 →
SECURITY AGREEMENT Recorded Jan 18, 2011
From: OBAGI MEDICAL PRODUCTS, INC., A DELAWARE CORPORATION; OMP, INC., A DELAWARE CORPORATION
To: COMERICA BANK, AS AGENT, A TEXAS BANKING ASSOCIATION
Reel/Frame 025647/0957 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 3, 2010
From: HATTENDORF, JUDY; CARLSON, STEVE
To: OMP, INC.
Reel/Frame 024779/0226 →
Continuity (2)
Provisional Application 61003015 · Nov 14, 2007
Related Publication 20100303747A1 · Dec 2, 2010