IP Library Granted Patent US 10,299,887
Granted Patent B2
US 10,299,887 · App. 12/766,602 · Granted May 28, 2019

Atmospheric non-thermal gas plasma method for dental surface treatment

Inventors: Qingsong Yu (Columbia, MO); Hao Li (Columbia, MO); Meng Chen (Columbia, MO)
Assignees: Nanova, Inc.; Curators of the University of Missouri Office of Intellectual Property Admin.
A61C5/30A61C5/00A61C13/0001
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Quick Facts
Patent No.
US 10,299,887
App. No.
12/766,602
Granted
May 28, 2019
Kind
B2
Abstract

The provision of dental restorations can be improved by generating a cold atmospheric plasma inside the mouth of the patient and then applying that cold atmospheric plasma onto a dental restoration site. The dental restoration site can be composed of either or both of dentin and enamel. Further, the provision of dental restorations can also be improved by introducing a dental adhesive onto a dental restoration site and treating it with a cold atmospheric plasma.

Claims (44)

1. A method of increasing bonding strength on a dental restoration site in the mouth of a patient comprising:

removing material from the dental restoration site to expose a surface comprising dentin;

generating a cold atmospheric plasma inside the mouth of the patient, said plasma having a brush-like shape;

after the step of removing material to expose the dentin, applying the cold atmospheric plasma onto the dental restoration site for a period of time between about 30 seconds and 60 seconds to chemically activate the dentin to increase penetration of a dental adhesive into collagen fibrils of the dentin and increase chemical bonding between the collagen fibrils and the dental adhesive;

wherein said dental adhesive is a composite material and wherein said cold atmospheric plasma comprises argon;

after the step of applying the plasma, applying the adhesive to the surface; and

installing a dental restoration on the adhesive-coated surface.

2. The method of claim 1 wherein the dental restoration site comprises a surface of dentin.

3. The method of claim 1 wherein the dental restoration site comprises a surface of enamel.

4. The method of claim 1 wherein the dental restoration site comprises a surface of dental adhesive.

5. The method of claim 1 wherein the dental restoration site comprises a surface of dental composite layers.

6. The method of claim 1 wherein the temperature of the cold atmospheric plasma is between about 35° C. and about 39° C.

7. The method of claim 1 wherein the cold atmospheric plasma comprises plasma gases selected from the group consisting of argon, oxygen, gaseous hydrocarbons, and mixtures thereof.

8. The method of claim 1 where the cold atmospheric plasma is applied to the periphery of a dental restoration site.

9. The method of claim 1 , wherein the plasma is applied onto a dental restoration site for a period of time of about 30 seconds.

10. The method of claim 1 , wherein said cold atmospheric plasma consists essentially of argon.

11. A method of installing a dental restoration on a tooth inside of a patient's mouth comprising:

exposing a surface comprising dentin;

treating the surface with a dentally acceptable acid;

removing the dentally acceptable acid from the surface;

providing a plasma generator;

generating a cold atmospheric plasma inside the mouth of the patient with the plasma generator, said plasma having a brush-like shape;

after the steps of removing the material from the tooth and removing the acid from the surface, chemically activating the dentin by applying the cold atmospheric plasma onto the surface for a period of time between about 30 seconds and 60 seconds to increase penetration of a dental adhesive into collagen fibrils of the dentin and increase chemical bonding between the collagen fibrils and the dental adhesive;

after the step of chemically activating the dentin by applying the plasma, coating the dental adhesive on the surface;

wherein said dental adhesive is a composite material and

installing a dental restoration on the adhesive-coated surface.

12. The method of claim 11 comprising, in addition:

generating a cold atmospheric plasma jet inside the mouth of the patient with the plasma generator; and

applying the cold atmospheric plasma jet onto the adhesive-coated surface.

13. The method of claim 11 wherein the temperature of the cold atmospheric plasma is between about 35° C. and about 39° C.

14. The method of claim 11 wherein the cold atmospheric plasma comprises plasma gases selected from the group consisting of argon, oxygen, gaseous hydrocarbons, and mixtures thereof.

15. The method of claim 11 wherein the application of cold atmospheric plasma onto the surface results in an increase of carbonyl groups present on the surface for increasing the hydrogen bonding strength between the dental adhesive and collagen fibrils of the dentin.

16. The method of claim 11 , wherein said cold atmospheric plasma consists essentially of argon.

17. A method of increasing bonding strength on a dental restoration site in the mouth of a patient comprising:

exposing a surface comprising dentin;

treating the surface with a dentally acceptable acid;

removing the dentally acceptable acid from the surface;

generating a cold atmospheric plasma inside the mouth of the patient,

after the steps of removing the material from the tooth and removing the acid from the surface, chemically activating the dentin by applying the cold atmospheric plasma to expose amino acids and increase the exposed surface area of amino acids available for adhesion, the cold atmospheric plasma being applied at a temperature between about 35° C. and 39° C. onto the surface for a period of time between about 10 seconds and 60 seconds;

after the step of chemically modifying the surface by applying the plasma, coating the dental adhesive on the surface;

wherein said dental adhesive is a composite material and wherein said cold atmospheric plasma comprises argon; and

installing a dental restoration on the adhesive-coated surface.

18. The method of claim 17 , wherein said cold atmospheric plasma consists essentially of argon.

19. The method of claim 17 , wherein the plasma is applied onto a dental restoration site for a period of time of about 30 seconds.

Assignments (3)
CONFIRMATORY LICENSE Recorded May 20, 2010
From: UNIVERSITY OF MISSOURI COLUMBIA
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 024414/0054 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 23, 2010
From: YU, QUINGSONG; LI, HAO
To: THE CURATORS OF THE UNIVERSITY OF MISSOURI
Reel/Frame 024282/0490 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 23, 2010
From: CHEN, MENG
To: NANOVA, INC.
Reel/Frame 024282/0524 →
Continuity (2)
Provisional Application 61214450 · Apr 23, 2009
Related Publication 20100273129A1 · Oct 28, 2010