Reinforced absorbable synthetic matrix for hemostatic applications
The present invention is directed to a reinforced absorbable hemostat comprising at least one hemostatic agent in a single layer of nonwoven synthetic fabric having a mixture of compressed fiber staples of a polyglycolide/polylactide copolymer and a polydioxanone.
1. A synthetic hemostatic fabric comprising at least one hemostatic agent in a non-woven layer of a first absorbable fabric that comprises polyglycolide/polylactide copolymer and a second absorbable fabric that comprises polydioxanone, wherein both fabrics are in staple form.
2. The synthetic hemostatic fabric of claim 1 , where the first absorbable fabric consists essentially of a copolymer of glycolide/lactide at a 90/10 mol/mol composition.
3. The synthetic hemostatic fabric of claim 2 , where the first absorbable fabric comprises of staple having a length from about 0.75 to 2.5 inches.
4. The synthetic hemostatic fabric of claim 1 that is substantially free of any oxidized polysaccharide material and the hemostatic agent comprises thrombin.
5. The synthetic hemostatic fabric of claim 1 , where the staple is crimped.
6. The synthetic hemostatic fabric of claim 4 , where the second absorbable fabric comprises of staple having a length from 0.75 to 2.5 inches.
7. The synthetic hemostatic fabric of claim 6 , where the staple is crimped.
8. The synthetic hemostatic fabric of claim 4 , where the hemostatic agent further comprises fibrinogen.
9. The synthetic hemostatic fabric of claim 1 , where the weight ratio of the first fabric staples to the second fabric staples is 70:30.
10. The synthetic hemostatic fabric of claim 9 , where the mixture of the staples is compacted to a thickness of about 1.5 mm.
11. The synthetic hemostatic fabric of claim 10 , where the mixture of the staples is compacted to a density of about 100 mg/cc.