IP Library Granted Patent US 8,911,774
Granted Patent B2
US 8,911,774 · App. 12/781,983 · Granted Dec 16, 2014

Topical composition for anti-aging skin treatment using dual DNA repair mechanism and method of use

Inventor: Vincent C. Giampapa (Montclair, NJ)
Assignee: Cellhealth Technologies Ltd.
A61K36/31A61K8/14A61K8/41A61K8/46A61K8/466A61K8/4986A61K8/60A61K8/63A61K8/676A61K8/678A61K8/97A61K36/48A61K36/484A61K36/74A61K36/899A61Q19/08A61K2800/592
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Quick Facts
Patent No.
US 8,911,774
App. No.
12/781,983
Granted
Dec 16, 2014
Kind
B2
Abstract

A topical composition for anti-aging treatment of the skin includes water soluble extract of Uncaria species, Arabidopsis thaliana extract, lipoic acid, dimethylethanolamine, tetrahexyldecyl ascorbate, dimethyl sulfoxide, Glycyrrhiza Glabra (Licorice) root extract, methylsulfonylmethane, phytosterols, D-ribose, tocotrienol, tocopherol, glucosamine hydrochloride, Pisum sativum extract; Bambusa vulgaris extract, and a dermatologically acceptable liposomal delivery medium. Further disclosed is a method using the topical composition for anti-aging skin treatment utilizing DNA repair in both the nucleus and the mitochondria. The topical composition can be applied on the skin of a person daily, and can also be applied in a dermal infusion treatment, with or without micro-dermal abrasion or skin suction. Topical application of the composition achieves effective reduction of pigmentation spots and degree of winkles, and improvement of skin color tone.

Claims (20)

1. A method of reducing pigmentation spots, treating wrinkles and improving skin color tone of skin in a person in need thereof comprising topically applying to one or more areas of the skin, an effective amount of a composition comprising:

(a) Arabidopsis thaliana extract in a concentration range from about 0.5% to about 2% (w/w);

(b) a water soluble extract of Uncaria species in a concentration range from about 0.5% to about 5% (w/w);

(c) alpha lipoic acid in a concentration range from about 1% to about 5% (w/w);

(d) dimethylethanolamine in a concentration range from about 0.2 to about 0.8% (w/w);

(e) tetrahexyldecyl ascorbate in a concentration range from about 0.5% to about 2% (w/w);

(f) dimethyl sulfoxide in a concentration range from about 0.5% to about 2% (w/w);

(g) Glycyrrhiza Glabra (Licorice) root extract in a concentration range from about 0.005% to about 0.3% (w/w);

(h) methylsulfonylmethane in a concentration range from about 0.1 to about 0.5% (w/w);

(i) phytosterols in a concentration range from about 0.1 to about 0.6% (w/w);

(j) D-ribose in a concentration range from about 0.01 to about 0.05% (w/w);

(k) a mixture of tocopherol and phytonutrients in an a concentration range of from about 0.5% to about 2% (w/w), wherein the phytonutrients are plant squalene, phyotsterols, co-enzyme Q10 and mixed carotenoids;

(l) a complex of Bambusa vulgaris extract, Pisum sativum extract and glucosamine hydrochloride in an amount of from about 0.5% to about 2% (w/w);

(m) a medium for delivering liposomes; and

(n) preservatives; and wherein the composition provides dual DNA repair.

2. The method of claim 1 , wherein said topical composition is topically applied to the one or more areas of skin one or more times daily.

3. The method of claim 1 , wherein said topical composition further comprises estriol.

4. The method of claim 1 , wherein the one or more areas of skin are on the forehead, eye area, perioral area, cheek, face, neck, chest or hands.

5. The method of claim 1 , wherein said topical composition is topically applied on the one or more areas of skin with dermal infusion.

6. The method of claim 1 , wherein the dermal infusion is micro-dermal abrasion or skin suction.

Assignments (4)
SECURITY INTEREST Recorded Jan 8, 2026
From: LIFE SCIENCE INSTITUTE, LLC
To: TRAILBLAZE HOLDINGS LLC
Reel/Frame 073412/0468 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2018
From: CELLHEALTH TECHNOLOGIES, LLC
To: LIFE SCIENCE INSTITUTE, LLC
Reel/Frame 047291/0692 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2014
From: GIAMPAPA, VINCENT, M.D.
To: LIFE SCIENCE INSTITUTE, LLC.
Reel/Frame 032337/0291 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2014
From: LIFE SCIENCE INSTITUTE, LLC.
To: CELLHEALTH TECHNOLOGIES LTD.
Reel/Frame 032337/0806 →
Continuity (2)
Provisional Application 61179112 · May 18, 2009
Related Publication 20100291190A1 · Nov 18, 2010