Implant and method for manufacturing same
The present invention relates to a method for manufacturing an implant, in particular an intraluminal endoprosthesis, with a body containing metallic material, preferably iron. The method includes the following steps to control degradation of the implant: (i) providing the body of the implant; and (ii) tribochemically treating at least part of the body surface by means of beam particles. An implant produced in this way is also described.
1. A method for manufacturing an implant, optionally an intraluminal endoprosthesis, having a body containing metallic material, optionally iron, comprising the following steps:
i) providing an implant body;
ii) micro-roughening a surface of the implant body by beaming electrically conductive particles against the implant body, wherein the electrically conductive particles adhere to the micro-roughened surface of the implant body, wherein the electrically conductive particles are selected from the group consisting of TiN, TiC, TiCN, and CuZn;
iii) tribochemically treating at least part of the micro-roughened surface by beaming granular salt particles against the micro-roughened surface to adhere the salt particles to the micro-roughened surface to initiate corrosion of the implant body under moist environmental conditions, wherein the salt particles are selected from the group consisting of NaCl, CaCl2, MgCl2 and dry-stored MgCl2; and
v) storing the implant body in an air free environment that temporarily prevents or reduces corrosion of the implant body by the adhered salt particles.
2. The method as claimed in claim 1 , wherein the step of tribochemically treating at least part of the micro-roughened surface comprises inserting the implant body into an installation comprising a jet nozzle in the form of a mandrel and sleeve such that the body surrounds the mandrel and the sleeve surrounds the body, and applying an electric field to the installation to accelerate the beam particles from the mandrel and towards the body, wherein the body has a different electric potential than the mandrel or the sleeve.
3. The method as claimed in claim 1 , wherein at least part of the implant body is tribochemically treated by beaming particles comprising a micro-encapsulated reagent, wherein the microencapsulation optionally has at least one thermo-, photolabile and/or mechanically labile predetermined breaking point.
4. The method as claimed in claim 1 , further comprising the step of applying a coating of magnesium stearate, parylene, a pharmaceutically active substance, zinc phosphates and/or hopeite crystals to at least part of the tribochemically treated surface of the implant body.
5. The method as claimed in claim 1 , wherein the average particle size of the beam particles is approximately 5 nm to approximately 20 μm.
6. The method as claimed in claim 1 , wherein the body of the implant is predominantly iron, optionally more than 90% by weight, optionally more than 99% by weight, optionally in an alloy.