Compressed chewing gum tablet
A compressed chewing gum tablet includes at least a first and a second chewing gum module, the first chewing gum module including a first chewing gum composition including at least a first active ingredient and chewing gum granules containing gum base, the second chewing gum module including a second chewing gum composition including at least a second active ingredient and chewing gum granules containing gum base, wherein the first active ingredient is a pharmaceutically active ingredient, and the second active ingredient is selected from the group consisting of pharmaceutically active ingredients and enhancers, wherein the gum base content of the first and second chewing gum modules is different.
1. A compressed chewing gum tablet comprising at least a first and a second chewing gum module,
said first chewing gum module comprising a first chewing gum composition comprising at least a first active ingredient and chewing gum granules containing gum base,
said second chewing gum module comprising a second chewing gum composition comprising at least a second active ingredient and chewing gum granules containing gum base,
wherein the first chewing gum composition is different in composition than the second chewing gum composition,
wherein said first active ingredient is nicotine and said second active ingredient is a pH control agent; and
wherein at least part of the pH control agent is contained within the second chewing gum module outside the chewing gum granules of the second chewing gum module, and wherein nicotine is contained within said chewing gum granules of the first chewing gum module.
2. The compressed chewing gum tablet according to claim 1 , wherein said first chewing gum composition comprises a further active ingredient different from said first active ingredient.
3. The compressed chewing gum tablet according to claim 1 , wherein said second chewing gum composition comprises a further active ingredient different from said second active ingredient.
4. The compressed chewing gum tablet according to claim 1 , wherein said active ingredients in said first chewing gum module are at least partly contained within said chewing gum granules.
5. The compressed chewing gum tablet according to claim 1 , wherein said active ingredients in said second chewing gum module are at least partly contained within said chewing gum granules.
6. The compressed chewing gum tablet according to claim 1 , wherein the gum base content of said first and secondary gum modules is different with respect to at least one of composition, weight, size of applied chewing gum granules, and degree of mixing with the active ingredient.
7. The compressed chewing gum tablet according to claim 1 , wherein at least one of said first and second chewing gum composition facilitates a bi-phasic release of said second active ingredient.
8. The compressed chewing gum tablet according to claim 1 , wherein said compressed chewing gum tablet comprises at least three individual coherent compressed modules.
9. The compressed chewing gum tablet according to claim 1 , wherein the chewing gum granules have been granulated to an average particle size of below 1500 μm and further grinded to an average particle size of below 800 μm.
10. The compressed chewing gum tablet according to claim 1 , wherein said chewing gum granules of the first chewing gum module comprise at least a part of said nicotine.