IP Library Granted Patent US 8,506,952
Granted Patent B2
US 8,506,952 · App. 12/829,520 · Granted Aug 13, 2013

Probiotic compositions and process thereof

Inventors: Kevin P. C. Minbiole (Dayton, VA); Reid Harris (Harrisonburg, VA)
Assignee: James Madison Innovations, Inc.
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,506,952
App. No.
12/829,520
Granted
Aug 13, 2013
Kind
B2
Abstract

Probiotic composition(s) and/or process(es) thereof. Processes may include applying Janthinobacterium , for example Janthinobacterium lividum , over a host and/or host area(s) to minimize microbe(s) and/or maximize therapeutic effects. A process to minimize a microbe may include applying to skin a composition including isolated Janthinobacterium lividum and a pharmaceutically acceptable carrier. Probiotic composition(s) and/or process(es) thereof may include relatively heat tolerant Janthinobacterium lividum which may produce metabolites, for example violacein up to approximately 29° C. Probiotic composition(s) and/or process(es) thereof may include Janthinobacterium lividum between approximately 25×10 6 and 6.4×10 7 cells. Probiotic composition(s) and/or process(es) thereof may include Janthinobacterium lividum which has and/or produces between approximately 18 μM and 129 μM of violacein. Probiotic composition(s) and/or process(es) thereof may include a stimulant to maximize metabolites. A process to minimize a microbe may include removing a portion of resident microbes with a sanitizer. Janthinobacterium lividum may be in lysed form.

Claims (16)

1. A process to minimize a microbe colony growth comprising applying to human skin a composition including isolated Janthinobacterium lividum and a pharmaceutically acceptable carrier.

2. The process of claim 1 , wherein the skin is human foot skin.

3. The process of claim 1 , wherein said microbe comprises at least one of bacteria, yeast, fungus and virus.

4. The process of claim 3 , wherein said fungus comprises Tricophyton rubrum.

5. The process of claim 1 , wherein said Janthinobacterium lividum produces violacein up to approximately 29° C.

6. The process of claim 1 , wherein said Janthinobacterium lividum comprises between approximately 25×10 6 and 6.4×10 7 cells per ml of said pharmaceutically acceptable carrier.

7. The process of claim 6 , wherein said Janthinobacterium lividum produces between approximately 18 μM and 129 μM of violacein.

8. The process of claim 1 , wherein said pharmaceutically acceptable carrier comprises at least one of an emulsion, paste, cream, lotion, gel, jelly, ointment, oil, aerosol, powder and solvent.

9. The process of claim 1 , wherein said composition comprises a stimulant to maximize at least violacein.

10. The process of claim 9 , wherein said stimulant comprises tryptophan.

11. The process of claim 1 , comprising applying a sanitizer to said skin prior to applying said composition.

12. The process of claim 11 , wherein said sanitizer comprises hydrogen peroxide.

13. The process of claim 1 , wherein said Janthinobacterium lividum is in a lysed form.

14. A process to minimize Tricophyton rubrum colony growth comprising applying to skin a composition including isolated Janthinobacterium lividum and a pharmaceutically acceptable carrier.

15. A process to minimize a microbe colony growth comprising applying to skin a composition including isolated Janthinobacterium lividum , a stimulant to maximize at least violacein, and a pharmaceutically acceptable carrier.

16. A process to minimize a microbe colony growth comprising applying to skin a composition including isolated Janthinobacterium lividum and a pharmaceutically acceptable carrier, wherein said Janthinobacterium lividum is in a lysed form.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 2, 2011
From: MINBIOLE, KEVIN P.; HARRIS, REID N.
To: JAMES MADISON UNIVERSITY
Reel/Frame 027160/0702 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 2, 2011
From: JAMES MADISON UNIVERSITY
To: JAMES MADISON INNOVATIONS, INC.
Reel/Frame 027160/0769 →
CONFIRMATORY LICENSE Recorded Aug 12, 2011
From: JAMES MADISON UNIVERSITY
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 026740/0980 →
CONFIRMATORY LICENSE Recorded Jan 3, 2011
From: JAMES MADISON UNIVERSITY
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 025574/0114 →
Continuity (2)
Provisional Application 61222964 · Jul 3, 2009
Related Publication 20110002891A1 · Jan 6, 2011