Methods and apparatus for buffering parenteral solutions
A system for transferring solutions from a first cartridge into a second cartridge comprises a cartridge holder, a plunger driver, and a cartridge connector. The cartridge connector carries a transfer needle and an exhaust needle. The cartridge holder positions the first cartridge against the cartridge connector so that the transfer needle penetrates the first cartridge septum. The second cartridge is removably inserted into another end of the cartridge connector so that both the transfer needle and the exhaust needle penetrate the second cartridge septum. The plunger driver is disposed to advance a plunger on the first cartridge to transfer solution from the first cartridge into the second cartridge thus displacing solution from the second cartridge through the exhaust needle. The cartridge connector includes a sealed interior waste chamber for receiving the solution from the second cartridge.
1. A method for buffering an anesthetic cartridge, said method comprising:
providing a buffer cartridge having a septum and a plunger;
providing a first anesthetic cartridge having a septum and a plunger;
attaching the buffer cartridge to one end of a cartridge connector so that a first end of a transfer needle penetrates the septum of the buffer cartridge;
attaching the first anesthetic cartridge to another end of the cartridge connector so that a second end of the transfer needle and a first end of an exhaust needle penetrate the septum of the anesthetic cartridge, wherein a second end of said exhaust needle opens to a sealed interior waste chamber in the cartridge connector; and
advancing the plunger on the buffer cartridge to transfer a volume of buffer from the buffer cartridge into the anesthetic cartridge and a volume of anesthetic from the anesthetic cartridge into the sealed interior waste chamber.
2. A method as in claim 1 , further comprising removing the anesthetic cartridge from the cartridge connector after the buffer has been transferred.
3. A method as in claim 2 , further comprising replacing the first anesthetic cartridge with a second anesthetic cartridge on said other end of the cartridge connector and further advancing the plunger to transfer an additional volume of buffer to the second anesthetic cartridge.
4. A method as in claim 3 , wherein additional anesthetic cartridges are sequentially replaced on the cartridge connector and volumes of buffer transferred to said additional anesthetic cartridges until the buffer cartridge is empty.
5. A method as in claim 1 , wherein the cartridge connector is disposed after the buffer cartridge is empty.
6. A method as in claim 1 , further comprising visually observing the buffer cartridge to determine when said buffer cartridge is empty.
7. A method as in claim 1 , wherein the cartridge connector is removably attached to a cartridge holder which holds the buffer.
8. A method as in claim 7 , wherein the cartridge holder has a window that allows visual observation of the contents of the buffer cartridge.
9. A device for transferring a volume of a solution from a first cartridge having a septum to another solution in a second cartridge having a septum, said device comprising:
a cartridge holder having a proximal end, a distal end, and a chamber for removably holding the first cartridge;
a plunger driver attachable to the proximal end of the cartridge holder and having a piston rod which engages a plunger on the first cartridge; and
a cartridge connector having a proximal end attachable to the distal end of the cartridge holder, a distal end adapted to engage a septum end of the second cartridge, and a sealed interior waste chamber, said cartridge connector including a transfer needle and an exhaust needle which extend distally to penetrate the septum end of the second cartridge, wherein the transfer needle extends proximally to penetrate the septum of the first cartridge and the exhaust needle terminates in the sealed interior waste chamber.
10. A device as in claim 9 , wherein the cartridge holder has a cylindrical body with a window to allow visual observation of the contents of a cartridge in the cartridge holder.
11. A device as in claim 10 , wherein a distal region of the cylindrical body is enlarged to removably receive the cartridge connector.
12. A device as in claim 9 , wherein the plunger driver is adjustable so that the length of travel of the piston rod can be selected prior to advancement of said piston rod.
13. A device as in claim 9 , wherein the cartridge connector comprises a cylindrical body that is removably received within the enlarged distal region of the cartridge holder.
14. A device as in claim 13 , wherein the sealed interior waste chamber is defined between spaced-apart wells in the cylindrical body of the cartridge connector.
15. A device as in claim 14 , wherein the first end of the cylindrical body forms a cylindrical sleeve which surrounds the exposed ends of the exhaust needle and the transfer needle, wherein said sleeve is adapted to receive the septum end of a cartridge.
16. A device as in claim 13 , wherein the first end of the transfer needle is axially spaced-apart from the first end of the exhaust needle.
17. A device as in claim 16 , wherein the transfer needle passes axially through the sealed interior waste chamber.
18. A device as in claim 17 , wherein the second end of the transfer needle is free of surrounding structure, said connector further including a removable cap for placing over the exposed second end of the transfer needle.
19. A cartridge connector for providing fluid transfer paths between a first cartridge having a septum and a second cartridge having a septum, said cartridge connector comprising:
a body having a first end, a second end and a sealed interior waste chamber;
a transfer needle having a first end exposed at the first end of the body and a second end exposed at the second end of the body, wherein both the first and second ends of the transfer needle are capable of penetrating a cartridge septum; and
an exhaust needle having a first end exposed at the first end of the body and a second end terminating in the sealed interior waste chamber, wherein the first end of the exhaust needle is capable of penetrating a cartridge septum.
20. A cartridge connector as in claim 19 , wherein the first end includes a cylindrical sleeve surrounding the exposed ends of the transfer needle and the exhaust needle, wherein the sleeve is adapted to receive the septum end of a cartridge.
21. A cartridge connector as in claim 20 , wherein the first end of the transfer needle is axially spaced-apart from the first end of the exhaust needle.
22. A cartridge connector as in claim 21 , wherein the transfer needle passes axially through the sealed interior waste chamber.
23. A cartridge connector as in claim 22 , wherein the second end of the transfer needle is free of surrounding structure, said connector further including a removable cap for placing over the exposed second end of the transfer needle.