IP Library Granted Patent US 9,555,171
Granted Patent B2
US 9,555,171 · App. 12/894,271 · Granted Jan 31, 2017

Methods and devices for collecting separate components of whole blood

Inventors: Mehmet Ziya Sengun (Raynham, MA); William Parrish (Raynham, MA); Brooks J. Story (Raynham, MA); Kristian DiMatteo (Raynham, MA); Gregory R. Whittaker (Raynham, MA); Douglas Allen Fifolt (Raynham, MA)
Assignee: DEPUY MITEK, LLC
A61M1/029A61M1/3693B01L3/5021A61M2202/0427B01D21/262B01D2221/10B01L2300/028B01L2400/0409B01L2400/0478B01L2400/0622
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Quick Facts
Patent No.
US 9,555,171
App. No.
12/894,271
Granted
Jan 31, 2017
Kind
B2
Abstract

A method provides for procuring platelet rich plasma (PRP) from a sample of whole blood in a vial. The method includes the steps of: separating the whole blood into layers through centrifugation with an upper layer containing platelet poor plasma (PPP) and a PRP layer below the upper layer containing PRP; adjusting an end point of a first range of motion of an extractor relative to a position of the PRP layer; moving the extractor through the first range of motion through the vial, PPP passing out from the upper layer through the extractor; and after the extractor reaches the end point of the first range of motion, extracting the PRP through the extractor and collecting the PRP.

Claims (14)

1. A method for procuring platelet rich plasma (PRP) from a sample of whole blood in a vial, the method comprising the steps of:

separating the whole blood into layers through centrifugation with an upper layer containing platelet poor plasma (PPP) and a PRP layer disposed below the upper layer and containing PRP;

adjusting an end point of a first range of motion of an extractor relative to a position of the PRP layer by setting the position of a stop against which an abutment associated with the extractor engages at the end point, the position of the stop being determined by aligning with the PRP layer an indicator associated with the stop;

moving the extractor through the first range of motion through the vial, PPP passing out from the upper layer through the extractor; and

after the extractor reaches the end point of the first range of motion, extracting the PRP through the extractor and collecting the PRP.

2. The method of claim 1 wherein the sample of whole blood is collected from a patient and further comprising the step of applying the PRP to a site on the patient's body to promote healing.

3. The method of claim 1 wherein the extractor comprises a piston sized to tightly fit through the vial and wherein the PPP passes out of the upper layer through an orifice in the piston.

4. The method of claim 3 wherein the step of extracting the PRP comprises passing a tip of a needle through the orifice to the PRP layer and extracting the PRP through the needle.

5. The method of claim 3 wherein the step of extracting the PRP comprises moving the piston beyond the end point of the first range of motion through a second range of motion and passing the PRP through the orifice while moving the extractor through the second range of motion.

6. The method of claim 5 wherein the orifice is disposed at a distal tip of a needle in the extractor.

7. The method of claim 5 wherein a handle is associated with the extractor and a user in one continuous motion, by pressing on the handle, moves the extractor through the first range of motion and the second range of motion.

8. The method of claim 5 and further comprising the step of passing the PPP through a first flow path as the extractor moves through the first range of motion and engaging a diverter as the extractor reaches the end point, the diverter sending the PRP through a separate second flow path.

9. The method of claim 8 wherein an abutment associated with the extractor engages a lever on the diverter as the extractor reaches the end point to send flow from the extractor through the second flow path.

10. The method of claim 9 wherein the diverter comprises a three-way valve.

Assignments (9)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2019
From: SYNTHES USA, LLC
To: DEPUY SPINE, LLC
Reel/Frame 048829/0673 →
CHANGE OF NAME Recorded Jan 31, 2019
From: DEPUY SYNTHES PRODUCTS, LLC
To: DEPUY SYNTHES PRODUCTS, INC
Reel/Frame 048198/0563 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2019
From: DEPUY MITEK HOLDING CORPORATION
To: SYNTHES USA, LLC
Reel/Frame 048198/0860 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2019
From: DEPUY MITEK, LLC
To: DEPUY SYNTHES SALES, INC.
Reel/Frame 048197/0069 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2019
From: DEPUY SYNTHES SALES INC.
To: DEPUY SYNTHES PRODUCTS, INC.
Reel/Frame 048197/0142 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2019
From: DEPUY MITEK, LLC
To: DEPUY MITEK HOLDING CORPORATION
Reel/Frame 048197/0861 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2019
From: DEPUY SPINE, LLC
To: DEPUY SYNTHES PRODUCTS, LLC
Reel/Frame 048198/0497 →
CHANGE OF NAME Recorded May 28, 2013
From: DEPUY MITEK, INC.
To: DEPUY MITEK, LLC
Reel/Frame 030492/0879 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 15, 2010
From: SENGUN, MEHMET ZIYA; PARRISH, WILLIAM; STORY, BROOKS J.; DIMATTEO, KRISTIAN; WHITTAKER, GREGORY R.; FIFOLT, DOUGLAS ALLEN
To: DEPUY MITEK, INC.
Reel/Frame 025502/0983 →
Continuity (1)
Related Publication 20120082652A1 · Apr 5, 2012