IP Library Granted Patent US 9,566,177
Granted Patent B2
US 9,566,177 · App. 12/899,425 · Granted Feb 14, 2017

Bioresorbable vascular implant having homogenously distributed stresses under a radial load

Inventor: Machiel van der Leest (Paris, FR)
Assignee: Artertial Remodeling Technologies, S.A.
A61F2/915A61F2/91A61F2210/0004
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Quick Facts
Patent No.
US 9,566,177
App. No.
12/899,425
Granted
Feb 14, 2017
Kind
B2
Abstract

A bioresorbable vascular implant for implantation in a bodily lumen has a tubular framework and includes one or more annular support members. Each of the one or more annular support members includes a plurality of struts interconnected by a hinge region. Each of the plurality of struts also includes a mid-section. The vascular implant also includes at least one viscoelastic material that enables transition of the vascular implant between a collapsed configuration and an expanded configuration. Each of the plurality of struts and the hinge region defines a cross-section. The moment of inertia increases from the mid-section towards the hinge region to accommodate the transition and resist a radial load applied to the vascular implant in the expanded configuration.

Claims (33)

1. A bioresorbable vascular implant having a tubular framework and being for implantation in a bodily lumen, said vascular implant comprising:

one or more annular support members, each of said one or more annular support members including a plurality of struts interconnected by a hinge region having a width, each of said plurality of struts including a mid-section having a width;

wherein said vascular implant is comprised of at least one viscoelastic material that enables transition of said vascular implant between a collapsed configuration and an expanded configuration, each of said plurality of struts and said hinge region defining a cross-section;

wherein the moment of inertia increases from each said mid-section towards each said hinge region to accommodate said transition and resist a radial load applied to said vascular implant in the expanded configuration;

wherein the width of each of said plurality of struts tapers substantially continuously from each said hinge region to each said mid-section; and

wherein stresses between said mid-section of said plurality of struts and said hinge region are evenly distributed under application of the radial load to said vascular implant in the expanded configuration.

2. The bioresorbable vascular implant of claim 1 , wherein said vascular implant is a scaffold.

3. The bioresorbable vascular implant of claim 1 , wherein said vascular implant is a stent.

4. The bioresorbable vascular implant of claim 1 , wherein the cross-section defines a width.

5. The bioresorbable vascular implant of claim 1 further comprising at least one cross-strut intersecting said one or more annular support members.

6. The bioresorbable vascular implant of claim 5 , wherein the width of said at least one cross-strut is less than the width of said hinge region.

7. The bioresorbable vascular implant of claim 5 , wherein said at least one cross-strut breaks in less than about 90 days due to degradation of the viscoelastic material comprising said at least one cross-strut following implantation of said vascular implant in the bodily lumen.

8. The bioresorbable vascular implant of claim 1 , wherein said viscoelastic material comprises a thermoplastic polymer.

9. The bioresorbable vascular implant of claim 8 , wherein the glass transition temperature of said thermoplastic polymer is at least about 37° C.

10. The bioresorbable vascular implant of claim 9 , wherein said thermoplastic polymer is a polylactic acid (PLA) polymer.

11. The bioresorbable vascular implant of claim 10 , wherein said PLA polymer is poly-DL-lactic acid.

12. The bioresorbable vascular implant of claim 1 , wherein the width of each said hinge portion is about 250 μm or greater, and the width of each said mid-section is about 150 μm or greater.

13. The bioresorbable vascular implant of claim 12 , wherein the width of each said hinge portion is about 300 μm, and the width of each said mid-section is about 160 μm.

14. A bioresorbable vascular implant having a tubular framework and being for implantation in a bodily lumen, said vascular implant comprising:

one or more annular support members, each of said one or more annular support members including a plurality of struts interconnected by a hinge region having a width, each of said plurality of struts including a mid-section having a width; and

at least one cross-strut intersecting said one or more annular support members;

wherein said vascular implant is comprised of at least one viscoelastic material that enables transition of said vascular implant between a collapsed configuration and an expanded configuration, each of said plurality of struts and said hinge region defining a cross-section;

wherein the moment of inertia increases from each said mid-section towards each said hinge region to accommodate said transition and resist a radial load applied to said vascular implant in the expanded configuration;

wherein the width of each of said plurality of struts tapers substantially continuously from each said hinge region to each said mid-section;

wherein stresses between said mid-section of said plurality of struts and said hinge region are evenly distributed under application of the radial load to said vascular implant in the expanded configuration; and

wherein said at least one cross-strut breaks in less than about 90 days due to degradation of the viscoelastic material comprising said at least one cross-strut following implantation of said vascular implant in the bodily lumen.

15. A bioresorbable vascular implant having a tubular framework and being for implantation in a bodily lumen, said vascular implant comprising:

one or more annular support members, each of said one or more annular support members including a plurality of struts interconnected by a hinge region having a width, each of said plurality of struts including a mid-section having a width;

wherein said vascular implant is comprised of at least one viscoelastic material that enables transition of said vascular implant between a collapsed configuration and an expanded configuration, each of said plurality of struts and said hinge region defining a cross-section;

wherein the moment of inertia increases from each said mid-section towards each said hinge region to accommodate said transition and resist a radial load applied to said vascular implant in the expanded configuration;

wherein the width of each of said plurality of struts tapers substantially continuously from each said hinge region to each said mid-section;

wherein stresses between said mid-section of said plurality of struts and said hinge region are evenly distributed under application of the radial load to said vascular implant in the expanded configuration; and

wherein the vascular implant is configured for use in an angioplasty procedure.

Assignments (3)
CHANGE OF NAME Recorded Aug 10, 2021
From: SAHAJANAND MEDICAL TECHNOLOGIES PRIVATE LIMITED
To: SAHAJANAND MEDICAL TECHNOLOGIES LIMITED
Reel/Frame 057142/0759 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 1, 2019
From: ARTERIAL REMODELLING TECHNOLOGIES S.A.
To: SAHAJANAND MEDICAL TECHNOLOGIES PRIVATE LIMITED
Reel/Frame 049050/0571 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 20, 2011
From: VAN DER LEEST, MACHIEL
To: ARTERTIAL REMODELING TECHNOLOGIES, S.A.
Reel/Frame 025665/0079 →
Continuity (2)
Provisional Application 61249010 · Oct 6, 2009
Related Publication 20110112626A1 · May 12, 2011