IP Library Granted Patent US 9,149,514
Granted Patent B2
US 9,149,514 · App. 12/905,135 · Granted Oct 6, 2015

Composition and method for treating papilloma virus and equine sarcoids

Inventor: Stefano Ferrari (Rhinebeck, NY)
Assignee: MURAMI PHARMA, INC
A61K38/47
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Quick Facts
Patent No.
US 9,149,514
App. No.
12/905,135
Granted
Oct 6, 2015
Kind
B2
Abstract

A composition of lysozyme and a pharmaceutically acceptable carrier is active against the papilloma virus in both humans and animals. The composition can be used to treat women suffering from cervical cancer. The composition can also be used to treat cows and horses suffering sarcoids.

Claims (15)

1. A pharmaceutical composition for treating a papilloma virus infection in a mammal, said composition comprising (A) an antivirally effective amount of a lysozyme, (B) at least one additional therapeutic agent effective against papilloma virus and (C) a pharmaceutically acceptable carrier.

2. The pharmaceutical composition according to claim 1 , wherein the lysozyme is a human recombinant lysozyme.

3. The pharmaceutical composition according to claim 1 , wherein the lysozyme is a non-human lysozyme.

4. The pharmaceutical composition according to claim 3 , wherein the non-human lysozyme is a hen egg white lysozyme.

5. The pharmaceutical composition according to claim 1 , wherein the additional therapeutic agent effective against papilloma virus is acyclovir.

6. The pharmaceutical composition according to claim 1 , wherein the additional therapeutic agent effective against papilloma virus is cisplatin.

7. The pharmaceutical composition according to claim 1 , which is in the form of a cream, lotion, powder, gel, or sprayable or injectable solution.

8. The pharmaceutical composition according to claim 7 , which is in the form of a solution.

9. The pharmaceutical composition according to claim 7 , which is in the form of a topical cream or lotion.

10. A method of treating a papilloma virus infection in a patient in need thereof, said method comprising administering to said patient an effective amount therefor of a pharmaceutical composition according to claim 1 for a period of time sufficient to treat said papilloma virus infection.

11. The method according to claim 10 , wherein the patient is a human.

12. The method according to claim 11 , wherein the human is a woman suffering from or susceptible to cervical cancer.

13. The method according to claim 12 , wherein the lysozyme is administered to said woman in the form of tablets, capsules or lozenges.

14. The method according to claim 12 , wherein the lysozyme is administered to said woman in the form of an injectable solution.

15. The method according to claim 10 , wherein the patient is a bovine animal.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2013
From: BIOSEUTICA B.V.
To: MURAMI PHARMA, INC
Reel/Frame 031067/0280 →
CHANGE OF NAME Recorded Jul 17, 2012
From: RHODES HOLDING NETHERLANDS B.V.
To: BIOSEUTICA B.V.
Reel/Frame 028572/0319 →
MERGER Recorded Jul 16, 2012
From: SAINT SIMEON-MARKETING E INVESTIMENTOS LDA
To: RHODES HOLDING NETHERLANDS B.V.
Reel/Frame 028556/0324 →
Continuity (3)
Division 12039948 · Feb 29, 2008
Provisional Application 60892573 · Mar 2, 2007
Related Publication 20110027255A1 · Feb 3, 2011