IP Library Granted Patent US 8,293,535
Granted Patent B2
US 8,293,535 · App. 12/909,428 · Granted Oct 23, 2012

Bio-threat microparticle simulants

Assignee: Lawrence Livermore National Security, LLC
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Quick Facts
Patent No.
US 8,293,535
App. No.
12/909,428
Granted
Oct 23, 2012
Kind
B2
Abstract

A bio-threat simulant that includes a carrier and DNA encapsulated in the carrier. Also a method of making a simulant including the steps of providing a carrier and encapsulating DNA in the carrier to produce the bio-threat simulant.

Claims (49)

1. A bio-threat simulant, comprising:

a carrier and

DNA encapsulated in said carrier,

wherein said carrier is a carrier made of food additives.

2. The bio-threat simulant of claim 1 wherein said carrier is a carrier made of FDA approved food additives.

3. The bio-threat simulant of claim 1 wherein said carrier is a carrier made of kosher certified food additives.

4. The bio-threat simulant of claim 1 including a protein encapsulated in said carrier.

5. The bio-threat simulant of claim 1 wherein said carrier is a carrier made of food additives and including a protein combined with said food additives and said protein combined with said food additives encapsulated in said carrier.

6. The bio-threat simulant of claim 1 wherein said carrier is a carrier made of Glucono-delta lactone.

7. The bio-threat simulant of claim 1 including antibody triggers combined with and encapsulated in said carrier.

8. The bio-threat simulant of claim 1 including fluorescent molecules combined with and encapsulated in said carrier.

9. The bio-threat simulant of claim 1 including antibody triggers and fluorescent molecules combined with and encapsulated in said carrier.

10. The bio-threat simulant of claim 1 wherein said carrier has particle transport properties and including materials combined with and encapsulated in said carrier to alter the particle transport properties of said carrier.

11. The bio-threat simulant of claim 1 wherein said carrier has particle transport properties and including materials combined with and encapsulated in said carrier to alter the particle transport properties of said carrier wherein said materials to alter the particle transport properties are materials to alter charge.

12. The bio-threat simulant of claim 1 wherein said carrier has particle transport properties and including materials combined with and encapsulated in said carrier to alter the particle transport properties of said carrier wherein said materials to alter the particle transport properties are materials to alter density.

13. The bio-threat simulant of claim 1 wherein said carrier has materials to control particle transit properties and wherein said materials to control particle transit properties are combined with and encapsulated in said carrier to control particle transit properties of said carrier.

14. The bio-threat simulant of claim 1 including unique DNA.

15. A bio-threat simulant, comprising:

DNA, and

carrier means,

wherein said carrier means is a carrier means made of food additives and

wherein said DNA is encapsulated in said carrier means.

16. The bio-threat simulant of claim 15 wherein said carrier means is a carrier means made of FDA approved food additives.

17. The bio-threat simulant of claim 15 wherein said carrier means is a carrier means made of kosher certified food additives.

18. The bio-threat simulant of claim 15 including a protein encapsulated in said carrier means.

19. The bio-threat simulant of claim 15 wherein said carrier means is a carrier means made of food additives and including a protein combined with said food additives.

20. The bio-threat simulant of claim 15 including antibody triggers combined with and encapsulated in said carrier means.

21. The bio-threat simulant of claim 15 including fluorescent molecules combined with and encapsulated in said carrier means.

22. The bio-threat simulant of claim 15 including antibody triggers and fluorescent molecules combined with and encapsulated in said carrier means.

23. The bio-threat simulant of claim 15 wherein said carrier means has particle transport properties and including materials combined with and encapsulated in said carrier means to alter said particle transport properties of said carrier means.

24. The bio-threat simulant of claim 15 wherein said carrier means has particle transport properties and including materials combined with and encapsulated in said carrier means to alter said particle transport properties of said carrier means wherein said materials to alter said particle transport properties are materials to alter charge.

25. The bio-threat simulant of claim 15 wherein said carrier means has particle transport properties and including materials combined with and encapsulated in said carrier means to alter the particle transport properties of said carrier means wherein said materials combined with and encapsulated in said carrier means to alter said particle transport properties are materials to alter density.

26. The bio-threat simulant of claim 15 wherein said carrier means has materials to control particle transit properties and wherein said materials to control particle transit properties are combined with and encapsulated in said carrier means to control particle transit properties of said carrier means.

27. The bio-threat simulant of claim 15 including unique DNA.

28. A method of making a bio-threat simulant, comprising the steps of:

providing a carrier, wherein said carrier is a carrier made of food additives and encapsulating DNA in said carrier to produce the bio-threat simulant.

29. The method of making a bio-threat simulant of claim 28 wherein said carrier is a carrier made of FDA approved food additives.

30. The method of making a bio-threat simulant of claim 28 wherein said carrier is a carrier made of kosher certified food additives.

31. The method of making a bio-threat simulant of claim 28 further comprising the step of encapsulating a protein in said carrier.

32. The method of making a bio-threat simulant of claim 28 wherein said carrier is a carrier made of food additives and further comprising the step of encapsulating a protein in said carrier.

33. The method of making a bio-threat simulant of claim 28 further comprising the step of encapsulating antibody triggers in said carrier.

34. The method of making a bio-threat simulant of claim 28 further comprising the step of encapsulating fluorescent molecules in said carrier.

35. The method of making a bio-threat simulant of claim 28 further comprising the steps of encapsulating antibody triggers in said carrier and encapsulating fluorescent molecules in said carrier.

36. The method of making a bio-threat simulant of claim 28 wherein said carrier has particle transport properties and further comprising the step of encapsulating materials to alter said particle transport properties of said carrier in said carrier.

37. The method of making a bio-threat simulant of claim 28 wherein said carrier has particle transport properties and including the step of encapsulating materials to alter said particle transport properties of said carrier in said carrier wherein said materials to alter said particle transport properties are materials to alter charge.

38. The method of making a bio-threat simulant of claim 28 wherein said carrier has particle transport properties and further comprising the step of encapsulating materials to alter said particle transport properties of said carrier in said carrier wherein said materials to alter said particle transport properties are materials to alter density.

39. The method of making a bio-threat simulant of claim 28 wherein said carrier has particle transport properties and further comprising the step of encapsulating materials to control said particle transit properties of said carrier in said carrier.

40. The method of making a bio-threat simulant of claim 28 further comprising the step of encapsulating unique DNA in said carrier.

41. The method of making a bio-threat simulant of claim 28 further comprising the steps of aerosoling said carrier and said encapsulated DNA producing an aersol form of said carrier and said encapsulated DNA and using said carrier and said encapsulated DNA in said aerosol form.

Assignments (2)
CONFIRMATORY LICENSE Recorded Dec 9, 2010
From: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
To: U.S. DEPARTMENT OF ENERGY
Reel/Frame 025453/0560 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 9, 2010
From: FARQUAR, GEORGE ROY; LEIF, ROALD N.
To: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
Reel/Frame 025334/0227 →
Continuity (2)
Provisional Application 61257242 · Nov 2, 2009
Related Publication 20110104808A1 · May 5, 2011