IP Library Granted Patent US 8,486,348
Granted Patent B2
US 8,486,348 · App. 12/914,675 · Granted Jul 16, 2013

Channel and method of forming channels

Inventors: Leon M. Bellan (Somerville, MA); Harold G. Craighead (Ithaca, NY); Elizabeth A. Strychalski (North Potomac, MD)
Assignee: Cornell University
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Quick Facts
Patent No.
US 8,486,348
App. No.
12/914,675
Granted
Jul 16, 2013
Kind
B2
Abstract

A device is made by forming sacrificial fibers on a substrate mold. The fibers and mold are covered with a first material. The substrate mold is removed, and the covered fibers are then removed to form channels in the first material.

Claims (16)

1. A method comprising:

forming a mold to define microfluidic structures;

electrospinning nanofibers on the mold to connect the microfluidic structures;

forming a resin on top of the mold and nanofibers such that at least a portion of selected nanofibers is encapsulated in the resin;

removing the mold;

removing the nanofibers from the resin; and

capping the resin such that nanofibers form a fluidic connection between the microfluidic structures.

2. The method of claim 1 and further comprising coating the mold with a non-stick material prior to electrospinning the nanofibers.

3. The method of claim 1 wherein the nanofibers comprise polyethylene oxide.

4. The method of claim 1 wherein the resin comprises polydimethylsiloxane.

5. The method of claim 1 wherein the mold comprises a silicon substrate having patterned features to define two reservoirs separated by a gap.

6. A method comprising:

forming a mold to define microfluidic structures;

electrospinning nanofibers on the mold to connect the microfluidic structures;

forming a resin on top of the mold and nanofibers such that at least a portion of selected nanofibers is encapsulated in the resin; and

removing the nanofibers from the resin to form a fluidic connection between the microfluidic structures.

Assignments (3)
CONFIRMATORY LICENSE Recorded Jul 10, 2014
From: CORNELL UNIVERSITY RESEARCH FOUNDATION
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 033290/0371 →
CONFIRMATORY LICENSE Recorded May 19, 2011
From: CORNELL UNIVERSITY
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 026306/0978 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 11, 2011
From: BELLAN, LEON M.; CRAIGHEAD, HAROLD G.; STRYCHALSKI, ELIZABETH A.
To: CORNELL UNIVERSITY
Reel/Frame 025780/0086 →
Continuity (1)
Related Publication 20120107194A1 · May 3, 2012