IP Library › Granted Patent US 8,814,800
Granted Patent B2
US 8,814,800 · App. 12/915,496 · Granted Aug 26, 2014

Apparatus and method for enhancing and analyzing signals from a continuous non-invasive blood pressure device

Inventors: Jürgen Fortin (Graz, AT); Rupert Grüllenberger (Graz, AT)
Assignee: CNSystems Medizintechnik AG
A61B5/0059A61B5/7203A61B5/022A61B5/02241
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Quick Facts
Patent No.
US 8,814,800
App. No.
12/915,496
Granted
Aug 26, 2014
Kind
B2
Abstract

A system and method of enhancing a blood pressure signal is disclosed. The volume of an artery in a finger is measured by a photo-plesthysmographic (PPG) system, which produces a PPG signal. This PPG system is placed inside a cuff, and the cuff pressure is controlled by the PPG signal. The portion or component of the PPG signal having a frequency higher than a predefined threshold frequency is then modified or enhanced, such as by multiplying the high frequency component by a calibration factor. A blood pressure signal is then calculated using the cuff pressure and the modified PPG signal. A blood pressure contour curve may then be generated, and a variety of parameters may be calculated using the curve.

Claims (83)

1. A method for determining a blood pressure contour curve comprising:

placing a cuff having a photo-plethysmographic (PPG) system over an artery in a human finger, the PPG system producing a PPG signal based on volume of the artery, the PPG system including at least one light source and at least one light detector;

modifying, by a computing device, a component of the PPG signal having a frequency higher than a predefined threshold frequency by eliminating from the PPG signal an undesired portion of the PPG signal and reconstructing the PPG signal from the remaining portion of the PPG signal;

the cuff pressure being controlled by one or more components of the modified PPG signal; and

calculating, by the computing device, a blood pressure signal using at least the modified component of the PPG signal.

2. The method of claim 1 wherein a new blood pressure is calculated using the cuff pressure and the modified PPG signal.

3. The method of claim 2 wherein modifying a component of the PPG signal having a frequency higher than a predefined threshold frequency further comprises:

separating the PPG signal into a first component having a frequency higher than the predefined threshold frequency and a second component having a frequency lower than the predefined threshold frequency;

modifying the first component; and

adding the modified first component to the second component to create a modified PPG signal;

using the modified PPG signal and the cuff pressure to calculate the blood pressure signal.

4. The method of claim 2 wherein the modification further includes calibrating a component of the blood pressure signal having a frequency higher than a predefined threshold frequency using a value obtained for blood pressure by a sphygmomanometer placed on an artery in a human upper arm.

5. The method of claim 2 wherein the modification further includes multiplying a component of the blood pressure signal having a frequency higher than a predefined threshold frequency by a calibration factor, the calibration factor being calculated from a blood pressure measurement from a sphygmomanometer placed on an artery in a human upper arm.

6. The method according to claim 2 , wherein the threshold frequency is about 0.3 Hz.

7. The method according to claim 2 , wherein the calculation uses anthropometric parameters.

8. The method according to claim 2 , further comprising calculating physiological parameters from the blood pressure contour curve.

9. The method according to claim 8 , wherein the parameters are calculated by using multiport algorithms.

10. The method according to claim 8 , wherein the parameters are calculated by using one or more markers of input signals.

11. The method according to claim 1 , wherein the reconstruction is calculated from the pulsatile part of the remaining portion of the PPG signal.

12. The method according to claim 11 , wherein the reconstructed PPG signal is

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13. The method according to claim 1 , wherein the part of the PPG signal having the undesired portion of the PPG signal is below a predetermined frequency.

14. A device for determining a blood pressure contour curve comprising:

a pressure cuff adapted to be placed over an artery in a human finger, the cuff including a PPG system having at least one light source and at least one light detector;

a pressure sensor;

a controller for controlling the pressure in the cuff;

wherein the PPG system produces a PPG signal based on volume of the artery, a pressure signal is calculated by a computing device using the PPG signal, and the pressure signal is continuously applied to the cuff and finger;

wherein the computing device modifies a component of the PPG signal having a frequency higher than a predefined threshold frequency and calculates a blood pressure signal using the cuff pressure and the modified PPG signal; and

wherein the controller uses the one or more components of the modified PPG signal to control the pressure in the cuff.

15. The device according to claim 14 , wherein the computing device receives control state information from the controller.

16. The device according to claim 14 , wherein the computing device receives information from a calibration device.

17. The device according to claim 14 , wherein the computing device receives scaling information from another device.

18. The device according to claim 14 , where the computing device receives information from a hydrostatic correction system.

19. The device according to claim 12 , wherein the computing device receives anthropometric information from the patient.

20. The device according to claim 14 , wherein the computing device calculates physiological parameters from one or more input signals.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 29, 2010
From: FORTIN, JURGEN, DR.; GRULLENBERGER, RUPERT
To: CNSYSTEMS MEDIZINTECHNIK AG
Reel/Frame 025219/0341 →
Continuity (3)
Provisional Application 61256081 · Oct 29, 2009
Provisional Application 61256110 · Oct 29, 2009
Related Publication 20110105918A1 · May 5, 2011