Inhibitors of fatty acid amide hydrolase and monoacylglycerol lipase for modulation of cannabinoid receptors

Inventors: Alexandros Makriyannis (Watertown, MA); Lakshmipathi Pandarinathan (Shrewsbury, MA); Nikolai Zvonok (Revere, MA); Teija Parkkari (Kuopio, FI); Lauren Chapman (Waltham, MA)

Assignee: NORTHEASTERN UNIVERSITY

A61K31/41 A61K31/415 C07D231/12 C07D233/56 C07D235/08 C07D249/08 C07D249/18 C07D263/22 C07D401/12 C07D471/04 C07D473/00 C07D473/28 G01N21/6428

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Quick Facts

Patent No.: US 9,271,962
App. No.: 12/933,322
Granted: Mar 1, 2016
Kind: B2

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Abstract

Disclosed are compounds and compositions that inhibit the action of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGL), methods of inhibiting FAAH and MGL, methods of modulating cannabinoid receptors, and methods of treating various disorders related to modulation of cannabinoid receptors.

Claims (1)

1. A compound having the formula:

Assignments (4)

CONFIRMATORY LICENSE Recorded Mar 6, 2020

From: NORTHEASTERN UNIVERSITY

To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR

Reel/Frame 052117/0667 →

CONFIRMATORY LICENSE Recorded Nov 22, 2019

From: NORTHEASTERN UNIVERSITY

To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR

Reel/Frame 051097/0269 →

CONFIRMATORY LICENSE Recorded Dec 9, 2016