Granted Patent
B2
US 8,420,678 · App. 12/937,898 · Granted Apr 16, 2013
Small molecule inhibitors of the pleckstrin homology domain and methods for using same
Inventors:
Daruka Mahadevan (Tucson, AZ); Emmanuelle J. Meuillet (Oro Valley, AZ); Eugene A. Mash, Jr. (Tucson, AZ); Vijay M. Gohkale (Tucson, AZ); Garth Powis (Houston, TX); Shuxing Zhang (Pearland, TX)
Assignees:
Board of Regents, The University of Texas System; Arizona Board of Regents on Behalf of the University of Arizona
View Patent ↗
Loading inventors, assignments & file history…
Abstract
Pleckstrin homology domain binding compounds, pharmaceutical compositions including such compounds, and methods for their use are described herein.
Claims (6)
1. A compound of the formula:
or pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising a compound of the formula:
or pharmaceutically acceptable salt thereof; and
a pharmaceutically acceptable carrier or excipient.
3. The pharmaceutical composition of claim 1 , wherein said compound is present in an effective amount.
Assignments (4)
CONFIRMATORY LICENSE
Recorded Feb 13, 2015
From: UNIVERSITY OF ARIZONA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 034995/0653 →
CONFIRMATORY LICENSE
Recorded Oct 28, 2011
From: UNIVERSITY OF ARIZONA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 027143/0873 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 16, 2011
From: MAHADEVAN, DARUKA; MEUILLET, EMMANUELLE J.; MASH, EUGENE A., JR.; GOHKALE, VIJAY M.
To: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
Reel/Frame 025819/0849 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 16, 2011
From: POWIS, GARTH; ZHANG, SHUXING
To: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 025819/0996 →
Continuity (3)
Provisional Application
61124053
· Apr 14, 2008
Provisional Application
61199497
· Nov 17, 2008