Melanin promoting topical composition
The invention provides sunless tanning compositions for application to skin comprising an effective amount of at least one dopamine precursor, an effective amount of curcumin and a dermatologically acceptable carrier. Methods for preparation of said compositions are disclosed. When applied to the skin, the compositions may be used darken skin.
1. A sunless tanning composition for application to skin comprising: a melanin modulator that consists essentially of an effective amount of at least one dopamine precursor selected from tyrosine, N-Acetyl tyrosine and phenylalanine, and an effective amount of curcumin and a water-based dermatologically acceptable carrier.
2. The composition of claim 1 , wherein the dopamine precursor is present from about 1 to about 30 percent by weight of the tanning composition.
3. The composition of claim 2 , wherein the dopamine precursor is present from about 5 to about 20 percent by weight of the tanning composition.
4. The composition of claim 3 , wherein the dopamine precursor is present from about 10 to about 15 percent by weight of the tanning composition.
5. The cosmetic composition of claim 1 , wherein the dopamine precursor is N-Acetyl tyrosine.
6. The composition of claim 1 , wherein the dopamine precursor is a combination of N-Acetyl tyrosine and phenylalanine.
7. The composition of claim 1 , wherein the curcumin is present from about 0.05 to about 10 percent by weight of the tanning composition.
8. The composition of claim 7 , wherein the curcumin is present from about 1.0 to about 5 percent by weight of the tanning composition.
9. The composition of claim 8 , wherein curcumin is present at about 2.0 percent by weight of the tanning composition.
10. The composition of claim 1 , further comprising phenylisothiocyanate.
11. The composition of claim 10 , wherein the phenylisothiocyanate is present from about 0.5 to about 10.0 percent by weight of the tanning composition.
12. The composition of claim 11 , wherein the phenylisothiocyanate is present from about 1.0 to about 8.0 percent by weight of the tanning composition.
13. The composition of claim 12 , wherein the phenylisothiocyanate is present from about 2.0 to about 5.0 percent by weight of the tanning composition.
14. The composition of claim 1 , wherein the dermatologically acceptable carrier comprises one or more agents selected from the group consisting of: sodium hyaluronate, phosphatidylcholine, isopropyl palmitate, cetearyl alcohol, glycerol monostearate, shae butter, squalane, silicone and dimethyl ethanolamine.
15. The composition of claim 1 further comprising one or more agents selected from the group consisting of: α-hydroxy acids, caffeine, vitamin D3, quercertin, sulforaphanes, and a blend of magnesium aspartate and zinc gluconate and copper gluconate.
16. The composition of claim 1 , wherein the pH of the composition is in the range from about 2.5 to about 6.0.
17. The composition of claim 16 , wherein the pH of the composition is in the range from about 3.0 to about 5.5.
18. The composition of claim 17 , wherein the pH of the composition is in the range from about 3.8 to about 5.0.
19. The composition of claim 1 , wherein the composition is a lotion.
20. A sunless tanning composition comprising:
about 10 to about 15 percent by weight dopamine precursor;
about 1 to about 3 percent by weight curcumin; and
about 4 to about 6 percent by weight phenylisothiocyanate;
the balance being essentially water, wherein said dopamine precursor is selected from the group consisting of tyrosine, N-Acetyl tyrosine, phenylalanine, and mixtures thereof.
21. A method for preparing a water-based sunless tanning composition comprising a water phase, an oil phase, an aqueous DMAE mixture, an effective amount of a dopamine precursor selected from tyrosine, N-Acetyl tyrosine and phenylalanine, an effective amount of curcumin, and preservatives, comprising the steps of: adding the water phase to the oil phase; mixing the water phase with the oil phase; cooling to 38-40° C.; adding the DMAE mixture at temperature of about 38° C.; adding the dopamine precursors and curcumin to the resulting mixture at a temperature of about 35° C.; homogenizing; adding preservatives; and q.s. to 100.00 with water.
22. A method of darkening skin, the method comprising the step of administering to the skin a water-based composition comprising an effective amount of at least one dopamine precursor selected from tyrosine, N-Acetyl tyrosine and phenylalanine and an effective amount of curcumin acting in synergy with said dopamine precursor to upregulate melanin production.
23. The method of claim 22 , wherein the dopamine precursor is present from about 10 to about 15 percent by weight and the curcumin is present from about 1.0 to about 5 percent by weight.