IP Library Granted Patent US 8,530,423
Granted Patent B2
US 8,530,423 · App. 12/996,506 · Granted Sep 10, 2013

Anxiolytic compositions containing α

Inventors: Federique Balandras (Nancy, FR); Jean-Luc Gaillard (Luc sur Mer, FR); Francois Laurent (Nancy, FR); Yves Le Roux (Vandoeuvre-les-Nancy, FR); Laurent Miclo (Villers-les-Nancy, FR)
Assignee: Universite de Lorraine
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Quick Facts
Patent No.
US 8,530,423
App. No.
12/996,506
Granted
Sep 10, 2013
Kind
B2
Abstract

The invention relates to pharmaceutical compositions and food products containing peptides derived from the α s1 -casein in milk and having benzodiazepine-type activity and particularly, anxiolytic activity.

Claims (12)

1. A method of treating anxiety, sleep disorders and epilepsy comprising administering a composition comprising an effective amount of at least one peptide consisting of the sequence SEQ ID No: 1 or SEQ ID No: 2.

2. A method of treating anxiety, sleep disorders and epilepsy comprising administering a composition comprising a hydrolysate of casein α s1 -casein and/or a fraction of a hydrolysate of casein or α s1 -casein, containing an effective amount of at least one peptide consisting of the sequence SEQ ID No: 1 or SEQ ID No: 2.

3. The method of claim 1 , wherein the method treats anxiety.

4. The method of claim 1 , wherein the method treats sleep disorders.

5. The method of claim 1 , wherein the method treats epilepsy.

6. The method of claim 1 , wherein the peptide is produced by a recombinant organism.

7. The method of claim 6 , wherein the recombinant organism is selected from the group consisting of bacteria, yeast and a mammalian cell.

8. The method of claim 2 , wherein the method treats anxiety.

9. The method of claim 2 , wherein the method treats sleep disorders.

10. The method of claim 2 , wherein the method treats epilepsy.

11. The method of claim 2 , wherein the peptide is produced by a recombinant organism.

12. The method of claim 11 , wherein the recombinant organism is selected from the group consisting of bacteria, yeast and a mammalian cell.

Assignments (2)
MERGER Recorded Jul 16, 2012
From: INSTITUT NATIONAL POLYTECHNIQUE DE LORRAINE; UNIVERSITE DE NANCY
To: UNIVERSITE DE LORRAINE
Reel/Frame 028560/0905 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 15, 2011
From: BALANDRAS, FREDERIQUE; GAILLARD, JEAN-LUC; LAURENT, FRANCOIS; LE ROUX, YVES; MICLO, LAURENT
To: INSTITUT NATIONAL POLYTECHNIQUE DE LORRAINE; UNIVERSITE DE NANCY 1 HENRI POINCARE
Reel/Frame 025952/0459 →
Priority Claims (1)
FR 08 53757 · Jun 6, 2008 · national
Continuity (1)
Related Publication 20110312892A1 · Dec 22, 2011