Devices and methods for controlling patient temperature
Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed.
1. A system for controlling core body temperature of a subject and inducing systemic hypothermia, comprising:
a heat transfer tube configured for insertion within the esophagus of the subject, wherein the tube is configured to contact the epithelial lining of the esophagus;
an external heat exchanger containing a heat transfer fluid;
a pump for flowing the heat transfer fluid through a circuit within the heat transfer tube;
a heat transfer element in contact with the external heat exchanger;
a hollow tube having a distal end configured to extend into a stomach of the subject; and
a pressure transducer for generating a signal representative of abdominal or esophageal pressure, wherein the signal is transmitted to a microprocessor.
2. The system of claim 1 , wherein the microprocessor calculates an estimated transpulmonary pressure based on the esophageal pressure.
3. The system of claim 1 , wherein the microprocessor responds to the signal from the pressure transducer with a proportional integrated differential response to control mechanical ventilation.
4. The system of claim 1 , wherein the heat transfer tube comprises a heat transfer region capable of contacting substantially all of the esophageal epithelium.
5. The system of claim 1 , wherein the system is capable of cooling at a rate of about 1.2° C./hr to about 1.8° C./hr.
6. The system of claim 1 , wherein the system is capable of cooling a mass at a rate of about 350 kJ/hr to about 530 kJ/hr.
7. The system of claim 1 , wherein the system is capable of cooling a mass at a rate of about 430 kJ/hr.
8. The system of claim 1 , wherein the system includes a heat transfer region with a surface area of at least about 100 cm 2 .
9. The system of claim 8 , wherein the heat transfer region has a surface area of about 140 cm 2 .
10. The system of claim 1 , further comprising an ancillary tube, wherein the ancillary tube is insertable within the subject's nasopharynx or auricular canal, and wherein the ancillary tube includes a heat transfer medium flow channel.