IP Library › Patent Application 13025106
Patent Application
App. No. 13/025,106

PHENYLALKYL N-HYDROXYUREAS FOR TREATING LEUKOTRIENE RELATED PATHOLOGIES

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Quick Facts
Patent No.
US None
App. No.
13/025,106
Abstract

The method of treating patients by administering N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea for treatment of leukotriene related pathologies and compositions for this use.

Claims (5)

1 . A composition comprising N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea or pharmaceutically effective salts thereof wherein the compound comprises less than 2% of the S-enantiomer of N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea.

2 . The composition of claim 1 , wherein the composition comprises less than 1% of the S-enantiomer of N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propynyl]-N-hydroxyurea.

3 . The composition of claim 1 , wherein the composition is provided in a unit dosage form for oral administration and wherein the composition is present in an amount of about 100 mg.

4 . The composition of claim 3 , wherein said unit oral dosage form is a tablet or capsule.

5 . A method of treating a leukotriene related pathology in a subject in need thereof comprising administering the composition of claim 1 to the subject.

Assignments (8)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE'S ADDRESS PREVISOUSLY RECORDED ON REEL 027216 FRAME 0440.ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT OF ASSIGNORS INTEREST Recorded Jun 12, 2012
From: VIA, LLC
To: MADRIGAL PHARMACEUTICALS, INC.
Reel/Frame 028390/0021 →
COLLATERAL ASSIGNMENT OF PATENTS Recorded Mar 20, 2012
From: TALLIKUT PHARMACEUTICALS, INC.
To: BAY CITY CAPITAL FUND IV, L.P.
Reel/Frame 027897/0479 →
RELEASE OF SECURITY INTEREST Recorded Mar 20, 2012
From: BAY CITY CAPITAL FUND IV, L.P.
To: MADRIGAL PHARMACEUTICALS, INC.
Reel/Frame 027895/0978 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 20, 2012
From: MADRIGAL PHARMACEUTICALS, INC.
To: TALLIKUT PHARMACEUTICALS, INC.
Reel/Frame 027896/0235 →
COLLATERAL ASSIGNMENT OF PATENTS Recorded Nov 16, 2011
From: MADRIGAL PHARMACEUTICALS, INC.
To: BAY CITY CAPITAL FUND IV, L.P.
Reel/Frame 027241/0166 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 11, 2011
From: VIA PHARMACEUTICALS, INC.
To: VIA, LLC
Reel/Frame 027216/0375 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 11, 2011
From: VIA, LLC
To: MADRIGAL PHARMACEUTICALS, INC.
Reel/Frame 027216/0440 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 11, 2011
From: TAUB, REBECCA; BROTZ, TILMANN; FRANC, JOHN; COHEN, LARRY; PATEL, HEMANTKUMAR H.; CHEMBURKAR, SANJAY R.; SAWICK, DAVID P.
To: VIA PHARMACEUTICALS, INC.
Reel/Frame 026573/0159 →