IP Library Granted Patent US 8,387,402
Granted Patent B2
US 8,387,402 · App. 13/046,274 · Granted Mar 5, 2013

Methods and systems for cryogenic cooling

Inventors: Peter J. Littrup (Bloomfield Hills, MI); Alexei V. Babkin (Albuquerque, NM); Robert Duncan (Tijeras, NM); Sergey Boldarev (Moscow, RU)
Assignee: Cryodynamics, LLC
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Quick Facts
Patent No.
US 8,387,402
App. No.
13/046,274
Granted
Mar 5, 2013
Kind
B2
Abstract

Methods and systems are provided for cooling an object with a cryogen having a critical point defined by a critical-point pressure and a critical-point temperature. A pressure of the cryogen is raised above a pressure value determined to provide the cryogen at a reduced molar volume that prevents vapor lock. Thereafter, the cryogen is placed in thermal communication with the object to increase a temperature of the cryogen along a thermodynamic path that maintains the pressure greater than the critical-point pressure for a duration that the cryogen and object are in thermal communication.

Claims (50)

1. A system for cooling an object with a cryogen having a critical point defined by a critical-point pressure and a critical-point temperature, the system comprising:

a cryogen generator adapted to increase a pressure of the cryogen;

a valve provided at an outlet of the cryogen generator and adapted to release a flow of the cryogen when the pressure of the cryogen exceeds a predetermined pressure within the cryogen generator, the predetermined pressure being greater than a pressure value determined to provide the cryogen at a reduced molar volume that prevents vapor lock;

a cryogenic application device adapted to be brought into thermal communication with the object;

a conduit connecting the valve with the cryogenic application device for transporting the cryogen from the valve to the cryogenic application device; and

a flow controller to regulate flow of cryogen through the conduit and cryogenic application device,

wherein the cryogen increases in temperature when the application device is in thermal communication with the object along a thermodynamic path that maintains the pressure of the cryogen above the predetermined pressure for a duration that the application device and cryogen are in thermal communication.

2. The system recited in claim 1 wherein the cryogen generator comprises:

a thermally insulated tank having an interior volume for holding the cryogen; and

a heating element for applying heat within the interior volume.

3. The system recited in claim 2 wherein the heating element comprises a resistive heating element.

4. The system recited in claim 1 further comprising a bath of a second liquid cryogen surrounding a portion of the conduit between the valve and the cryogenic application device.

5. The system recited in claim 4 wherein the bath of the second liquid cryogen is at substantially ambient pressure.

6. The system recited in claim 4 wherein the cryogen and second cryogen are chemically identical.

7. The system recited in claim 1 wherein:

the cryogen generator comprises a plurality of cryogen generators, each of the plurality of cryogen generators being adapted to increase the pressure of the cryogen;

the valve comprises a plurality of valves, each of the plurality of valves being provided at an outlet of one of the plurality of cryogen generators and configured to release a flow of the cryogen when the pressure of the cryogen exceeds a predetermined pressure within the one of the plurality of cryogen generators;

the conduit is configured to provide selective connection between one of the plurality of valves and the cryogenic application device.

8. The system recited in claim 7 further comprising a liquid bath of the cryogen, wherein the plurality of cryogen generators are disposed within the liquid bath.

9. The system recited in claim 8 further comprising a plurality of heat exchangers, each such heat exchanger being disposed within the liquid bath of the cryogen and in fluid communication between a respective one of the plurality of cryogen generators and the conduit.

10. The system recited in claim 8 wherein each of the plurality of cryogen generators comprises an inlet to receive cryogen from the liquid bath of the cryogen.

11. The system recited in claim 1 wherein the cryogen is selected from the group consisting of N 2 , SF 6 , N 2 O, He, and CO 2 .

12. The system recited in claim 1 wherein the system is of a handheld size.

13. The system recited in claim 1 wherein the cryogenic application device comprises a detachable spray control nozzle.

14. The system recited in claim 13 wherein the detachable spray control nozzle comprises a vent adapted to release cryogen reflected during use of the cryogenic application device.

15. The system recited in claim 1 further comprising a thermometry device adapted to measure a temperature of the object.

16. A system for cooling an object with a cryogen having a critical point defined by a critical-point pressure and a critical-point temperature, the system comprising:

a container holding a liquid bath of the cryogen;

a plurality of cryogen generators disposed within the liquid bath, each such cryogen generator comprising:

a thermally insulated tank having an interior volume for holding the cryogen;

a heating element for applying heat within the volume; and

an inlet for selectively receiving cryogen from the liquid bath of the cryogen;

a plurality of valves, each such valve provided at an outlet of a respective one of the plurality of cryogen generators and adapted to release a flow of the cryogen when cryogen within the respective one of the plurality of cryogen generators exceeds a predetermined pressure greater than a pressure value determined to provide the cryogen at a reduced molar volume that prevents vapor lock; and

a conduit in fluid communication with each of the plurality of valves to selectively flow conduit from the cryogen generators in accordance with states of the valves.

17. The system recited in claim 16 further comprising a plurality of heat exchangers, each such heat exchanger disposed within the liquid bath and in fluid communication with a respective one of the plurality of cryogen generators and the conduit to provide heat exchange between cryogen flowing through the conduit from the respective one of the plurality of cryogen generators.

18. The system recited in claim 16 wherein the liquid bath is substantially at ambient pressure.

19. The system recited in claim 16 wherein the cryogen is selected from the group consisting of N 2 , SF 6 , N 2 O, He, and CO 2 .

20. A method for cooling an object with a cryogen having a critical point defined by a critical-point pressure and a critical-point temperature, the method comprising:

raising a pressure of the cryogen in a first cryogen generator above a pressure value determined to provide the cryogen at a reduced molar volume that prevents vapor lock;

thereafter, flowing the cryogen from the first cryogen generator to be in thermal communication with the object and to have a pressure greater than the determined pressure value while the cryogen and object are in thermal communication;

thereafter, raising a pressure of the cryogen in a second cryogen generator above the determined pressure value;

thereafter, flowing the cryogen from the second cryogen generator to be in thermal communication with the object and to have a pressure greater than the determined pressure value while the cryogen and object are in thermal communication; and

thereafter, replenishing cryogen in the first cryogen generator.

21. The method recited in claim 20 wherein flowing the cryogen from the first or second cryogen generator comprising flowing the cryogen through a conduit in thermal communication with a liquid cryogen bath to reduce a temperature of the cryogen.

22. The method recited in claim 21 wherein:

the cryogen and the liquid cryogen bath are chemically identical; and

replenishing cryogen in the first cryogen generator comprises replenishing cryogen from the liquid cryogen bath.

23. The method recited in claim 21 wherein the cryogen and liquid cryogen bath are selected from the group consisting of N 2 , SF 6 , N 2 O, He, and CO 2 .

24. The method recited in claim 20 wherein raising the pressure of the cryogen above the determined pressure value in the first and second cryogen generators comprises raising the pressure of the cryogen to near its critical-point pressure.

25. The method recited in claim 20 wherein raising the pressure of the cryogen above the determined pressure value in the first and second cryogen generators comprises applying heat within a thermally insulated tank at least until a predetermined pressure within the thermally insulated tank is reached.

Assignments (5)
SECURITY INTEREST Recorded Jul 31, 2024
From: ADAGIO MEDICAL HOLDINGS, INC.
To: ALLEGRO MANAGEMENT LLC
Reel/Frame 068236/0236 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2014
From: CRYODYNAMICS, LLC
To: ADAGIO MEDICAL, INC.
Reel/Frame 032187/0117 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 11, 2011
From: LITTRUP, PETER J.; BABKIN, ALEXEI V.; DUNCAN, ROBERT; BOLDAREV, SERGEY
To: MEDIPHYSICS LLP
Reel/Frame 025941/0006 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 11, 2011
From: MEDIPHYSICS LLP
To: CRYODYNAMICS, LLC
Reel/Frame 025941/0072 →
LICENSE Recorded Mar 11, 2011
From: CRYODYNAMICS, LLC
To: ENDOCARE, INC.
Reel/Frame 025946/0322 →
Continuity (9)
Division 11846226 · Aug 28, 2007
Division 10952531 · Sep 27, 2004
Continuation In Part 10757769 · Jan 14, 2004
Continuation In Part 13046274
Continuation 12018403 · Jan 23, 2008
Continuation In Part 10757768 · Jan 14, 2004
Provisional Application 60440662 · Jan 15, 2003
Provisional Application 60440541 · Jan 15, 2003
Related Publication 20110162390A1 · Jul 7, 2011