IP Library Granted Patent US 8,367,730
Granted Patent B2
US 8,367,730 · App. 13/097,045 · Granted Feb 5, 2013

Composition of amino acids for sublingual applying for enhanced skin integument repigmentation in vitiligo and method of its administration

Inventors: Irina Alekseevna Komissarova (Moscow, RU); Irina Markovna Korsunskaya (Moskovskaya, RE); Yaroslav Ryurikovich Nartsissov (Moscow, RU)
Assignee: Nekimmercheskoe Uchrezhdenie “Nauchno-Issledovatel'skij Institut Ttsitokhimii I Molekulyarnoyj Farmakologii”
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Quick Facts
Patent No.
US 8,367,730
App. No.
13/097,045
Granted
Feb 5, 2013
Kind
B2
Abstract

The task of this invention is in use of composition containing natural metabolites—amino acids, and in method of its administration which make it possible to increase skin repigmentation through sulfurcontaining compounds rise and activation of endogenic metabolic reactions, and to get persistent normalization of melanogenesis thus improving skin integument and as a consequence patient's quality of life. Composition includes L cystine, L glutamic acid and glycine in the following quantity, mg: L cystine 85 ± 10%, L glutamic acid 85 ± 10%, Glycine 85 ± 10% The amino acid composition mentioned above must be administered 3 times a day for 5 weeks independent of meal in accordance with method of increase of skin integument repigmentation in vitiligo. The course can be repeated in 4-5 weeks.

Claims (17)

1. A method for increasing skin integument repigmentation in vitiligo, said method comprising the steps of sublingually administering an amino acid composition comprising L cystine, L glutamic acid and glycine in the following amounts, mg:

L cystine

85 ± 10%,

L glutamic acid

85 ± 10%,

Glycine

85 ± 10%.

2. The method according to claim 1 , wherein said composition is in the form of a tablet, and the composition further comprises from 1% to 10%, by weight of the tablet, of cellulose ether and from 1% to 10%, by weight of the tablet, of stearate as excipients.

3. A method for increasing skin integument repigmentation in vitiligo, comprising the steps of sublingually administering an amino acid composition 3 times-a-day for a period of 5 weeks, said amino acid composition comprising L cystine, L glutamic acid and glycine in the following quantity, per single dose, mg:

L cystine

85 ± 10%,

L glutamic acid

85 ± 10%,

Glycine

85 ± 10%.

4. The method according to claim 3 , wherein the course of administering the composition is repeated after 4-5 months.

5. The method according to claim 3 , wherein the composition is administered in the form of a tablet or a powder obtained by porphyrizing a tablet.

Assignments (2)
CHANGE OF NAME Recorded Dec 29, 2014
From: NEKOMMERCHESKOE UCHREZHDENIE "NAUCHNO-ISSLEDOVATELJSKIYJ INSTITUT CITOKHIMII I MOLEKULYARNOYJ FARMAKOLOGII"
To: CHASTNOE UCHREZHDENIE "NAUCHNO-ISSLEDOVATELJSKIYJ INSTITUT CITOKHIMII I MOLEKULYARNOYJ FARMAKOLOGII"
Reel/Frame 034708/0245 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 24, 2011
From: KOMISSAROVA, IRINA ALEKSEEVNA; KORSUNSKAYA, IRINA MARKOVNA; NARTSISSOV, YAROSLAV RYURIKOVICH
To: NEKOMMERCHESKOE UCHREZHDENIE "NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT TSITOKHIMII I MOLEKULYARNOYJ FARMAKOLOGII'
Reel/Frame 026496/0610 →
Priority Claims (1)
EA 200900146 · Dec 26, 2008 · regional
Continuity (2)
Continuation PCTRU2009000701 · Dec 18, 2009
Related Publication 20110251279A1 · Oct 13, 2011