Tissue sampling tool
A sampling tool for isolating and collecting a tissue biopsy includes a hollow sampling cylinder that includes a first end and an opposing second end. The first end being a sharpened, annular cutting edge and a central bore extending completely from the first end to the second end. The sampling tool also includes a plunger having a first end and a second end. The plunger includes an air evacuation feature in the form of an air evacuation channel that extends from one end of the plunger to the other end and is open at both ends. The sampling tool has particular utility in isolating and collecting cylindrical core placental biopsies of a standardized size that can be used for multiple downstream applications, including the sampling of other harvested solid, soft-tissue organs such as brain, liver, kidney, and spleen.
1. A sampling tool for isolating and collecting a tissue sample comprising:
a hollow sampling cylinder that includes a first end and an opposing second end, the first end comprising a sharpened, circular cutting edge, wherein the hollow sampling cylinder includes a central bore extending completely from the first end to the second end, wherein an outer surface of the sampling cylinder includes a modified gripping surface; and
a plunger having a first end and a second end, the plunger being slidingly received within the hollow sampling cylinder and movable to a fully inserted position relative to the hollow sampling cylinder, the plunger including a shaft portion that terminates in the first end of the plunger, the plunger having a handle portion at the second end of the plunger, wherein the handle portion has greater dimensions than the shaft portion, wherein the first end of the plunger comprises a planar surface for contacting the tissue sample, wherein an outer surface of the shaft portion is in contact with an inner wall of the hollow sampling cylinder that defines the central bore, wherein the plunger includes at least one air evacuation feature constituted by a continuous channel formed through the plunger and extending from the first to second end of the plunger, the air evacuation feature being open at both the first and second ends of the plunger including being open along the planar surface at the first end of the plunger which defines a distalmost face of the plunger, wherein the planar face of the plunger comprises a distalmost structure of the sampling tool when the plunger is in the fully inserted position relative to the hollow sampling cylinder.
2. The sampling tool of claim 1 , wherein the sampling cylinder has a length of at least about 7.5 cm and a diameter of at least about 1.5 cm.
3. The sampling tool of claim 1 , wherein the bore has a cylindrical shape to isolate and collect a cylindrical core tissue sample.
4. The sampling tool of claim 1 , wherein the sampling cylinder and plunger are configured to cut and collect placental tissue.
5. The sampling tool of claim 1 , wherein the continuous channel is formed centrally within the plunger.
6. The sampling tool of claim 1 , wherein the sampling cylinder comprises a hollow plastic tube that includes an annular blade formed in in-situ with a body of the plastic tube, the annular blade defining the cutting edge.
7. The sampling tool of claim 1 , wherein the sampling cylinder comprises a hollow plastic tube that includes a linear blade formed at the first end, the linear blade extending less than a complete circumference of the tube.